B. (2003) Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane. Biochemistry 42, 13457-13467.Chiara DC, Dangott LJ, Eckenhoff RG, Cohen JB (2003) Identification of nicotinic acetylcholine recep- tor amino acids photolabeled by the volatile...
From the cycle of the Edman degradation in which radioactive residues are released, we conclude that Cys 192 and, possibly in addition, Cys 193 are the residues specifically labeled by 4-(N-maleimido)benzyltri[3H]methylammonium iodide. They are, therefore, close to the acetylcholine binding ...
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Synthesis and Preliminary Evaluation of 11 C-Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype?4.carbon-11muscarinic acetylcholine receptor subtype 4positive allosteric modulatorpositron emission tomographyVU0467485/AZ13713945...
et al. (2003) Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photo- labeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist. Biochemistry 42, 271- 283...
The 伪-conotoxins, obtained in nature from the venom of predatory marine snails, are a structurally related family of low mol. wt polypeptides which bind to the nicotinic acetylcholine receptor and cause rapid muscular paralysis and death in animals. These peptides contain 13-15 amino acids with...
Fluorescein isothiocyanate labeled α-cobratoxin: Interaction with acetylcholine receptor from Electrophorus electricus: S. Kang and A. Maelicke Max-Planck-Institut für Ernhrungsphysiologie, Dortmund, W-Germanydoi:10.1016/0041-0101(79)90083-7None...
nicotinic acetylcholine receptorfluorine-18positron emission tomographyEpibatidine ( exo -2-(2′-chloro-5′-pyridyl)-7-azabicyclo[2.2.1]heptane), a natural compound isolated from the skin of the Ecuadorian poison frog Epipedobates tricolor , is the most potent nicotinic acetylcholine receptor (nAChR...