Accumulating scientific evidence has revealed that targeting macrophage phenotypes might be a potentially effective therapy in DFUs because hyperglycemia increases the ratio of proinflammatory M1 to pro-regenerative M2 macrophages. Th...
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Innate immunity is the body's first line of defense against different pathogenic agents. Macrophages and neutrophils are two main cells that contribute significantly to innate and acquired immune responses, and important effector cells to destroy harmful agents. Function of these cells can be modulated...
To see if the cells flushed out of the nasal and sinus passages had turned on a generalized inflammatory response, the researchers compared specific genes used by immune system cells from the mice that breathed polluted air with the cells of those that breathed filtered air. They found higher l...
PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer. Nat. Immunol. 2020, 21, 442–454. [Google Scholar] [CrossRef] Pawłowska, A.; Kwiatkowska, A.; Suszczyk, D.; Chudzik, A.; Tarkowski, R.; Barczyński, B....