Cut-off value for absolute lymphocytes as an alternative for the immunophenotypic analysis of CD3+ T cells in the monitoring of immunosuppressive therapy with thymoglobulindoi:10.5935/0101-2800.20170032Gislaine FurlanettoAna AlegrettiMariela Farias
Multivariable logistic regression analysis showed that absolute counts of CD3+ T-lymphocytes < 524 cells/µl, CD3+ CD4+ < 369 cells/µl, and the number of T-lymphocyte subsets below the cutoff (T-lymphocyte subset index [TLSI]) were independent predictors of in-hospital mortality....
differentiating the total lymphocytes (CD45+), T lymphocytes (CD3+), and subtypes of T lymphocytes which comprise two subsets: cytotoxic T cells (T lymphocytes CD3+/CD8+) and helper
Graft CD3+ cell count Continuous, median (range) 18.79 (0-69.02) 21.16 (0-83.13) .20 ≤20.43, n (%)∗ 75 (56) 166 (48) .10 >20.43, n (%) 59 (44) 182 (52) ∗ Median of the whole cohort was taken as the cutoff point. Discussion The advent of early post-BMT interven...
Moreover, augmented numbers of p53-specific T cells coincided with high MHC class II expression in tumor cells but were inversely related to the T status of the tumor node metastasis staging system. Our results indicate the existence of natural immunosurveillance and tumor immune evasion, involving...
CD3+ dose of cells infused showed a weak but statistically significant correlation with ALC D30.doi:10.1016/j.bbmt.2019.12.399Jonathan LambirdHemant MurthyWilliam Paul SkeltonNosha FarhadfarJohn R. WingardBiology of Blood and Marrow Transplantation...
T cell dose ranged from 0.2 - 2 × 105 CD3+ cells/kg. GVHD prophylaxis was low dose cyclosporine (level 100-200 ng/ml) in 103 and standard dose in 54. Patients without ≥ grade II acute GVHD received 1-2 donor lymphocyte infusions between days 45 and 100. Median age was 34 years ...