Multivariable logistic regression analysis showed that absolute counts of CD3+ T-lymphocytes < 524 cells/µl, CD3+ CD4+ < 369 cells/µl, and the number of T-lymphocyte subsets below the cutoff (T-lymphocyte subset index [TLSI]) were independent predictors of in-hospital mortality....
Analysis demonstrated correlation between ALC and CD3 count. The Pearson correlation coefficient was 0.45 (R-Square 0.23),p less than0.0001. Validity testing of ALC of 200 cells/mm3against CD3 counts 100 cells/mm3showed sensitivity 0.635 (160/252), specificity 0.875 (70/80), positive predictive ...
000 cells/μL may give off an impression of being normal, but when considering the absolute value, this shows pathological basophilia with a high count of 1,000 cells/μL.
In pediatric patients, reaching a threshold of 50 CD4+ T cells per microliter by day 100 has been associated with improved overall survival.16-18 In adults, the minimum cell count that predicts improved outcomes is less well defined, but the total lymphocyte count has been associated with bette...
Cut-off value for absolute lymphocytes as an alternative for the immunophenotypic analysis of CD3+ T cells in the monitoring of immunosuppressive therapy with thymoglobulindoi:10.5935/0101-2800.20170032Gislaine FurlanettoAna AlegrettiMariela Farias
CD3+ dose of cells infused showed a weak but statistically significant correlation with ALC D30.doi:10.1016/j.bbmt.2019.12.399Jonathan LambirdHemant MurthyWilliam Paul SkeltonNosha FarhadfarJohn R. WingardBiology of Blood and Marrow Transplantation...
T cell dose ranged from 0.2 - 2 × 105 CD3+ cells/kg. GVHD prophylaxis was low dose cyclosporine (level 100-200 ng/ml) in 103 and standard dose in 54. Patients without ≥ grade II acute GVHD received 1-2 donor lymphocyte infusions between days 45 and 100. Median age was 34 years ...