过表达质粒目的 干细胞是当前研究的热门领域,利用干细胞定向分化作用可以促进神经损伤修复,但是干细胞具有分化方向不定和易老化的特点.本研究探究腺相关病毒(adeno associated virus,AAV)介导神经生长因子(nerve growth factor,NGF)过表达载体转染骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)对高强度聚焦...
As five hypoxia-responsive elements (5HRE) help to release NGF in hypoxia position long-lasting and specifically, the adeno-associated virus (AAV) serves as a vector, providing a platform for nutrition support and controlled expression. In an ideal condition, we expected NSCs could also repair ...
人物简介: 一、曾贞庆担任职务:曾贞庆目前担任晋安区贞庆五金店法定代表人;二、曾贞庆投资情况:目前曾贞庆投资晋安区贞庆五金店最终收益股份为0%;老板履历 图文概览商业履历 任职全景图 投资、任职的关联公司 商业关系图 一图看清商业版图 更新时间:2024-08-04...
Molecular TherapyBishop, Kathie M., et al. "527. CERE-110, an AAV2- based vector to deliver NGF, provides trophic activity to basal forebrain cholinergic neurons in rats and cynomolgous monkeys." Molecular Therapy 9 (2004): S199-S200....
539. Biodistribution and safety profile of CERE110 (AAV2NGF) delivered to the rodent braindoi:10.1016/j.ymthe.2004.06.667Mark LandersMelissa AustinKevin KwokKathie Bishop
Castle, Michael J.Baltanas, Fernando CalvoKovacs, ImreNagahara, Alan H.Bankiewicz, Krystof S.Barba, DavidTuszynski, Mark H.Elsevier ScienceAlzheimers & DementiaA. Blesch,Mark H. Tuszynski.NGF gene therapy for Alzheimer’’s disease. Experimental Neurology . 2006...