A549 is a lung cancer cell line with COSMIC ID: 905949 and Sanger ID: 369, and Cell Line Passport number SIDM00903 (Non-Small Cell Lung Cancer (NSCLC), Adenocarcinoma). The A549 cell line was established in 1972 by D.J. Giard et al, through an explant culture of adenocarcinomic lung ...
to culture A549 cells in different media over a long term and identify conditions for promoting alveolar type II differentiation characteristics in A549 cells[3] Perfil del ADN STR-PCR Data: Amelogenin: X,Y CSF1PO: 10,12 D13S317: 11 D16S539: 11,12 D5S818: 11 D7S820: 8,11 THO1:...
Characteristics Karyotype This is a hypotriploid human cell line with the modal chromosome number of 66, occurring in 24% of cells. Cells with 64 (22%), 65, and 67 chromosome counts also occurred at relatively high frequencies; the rate with higher ploidies was low at 0.4%. There were 6...
A number of the ultrastructural characteristics of A549 cells were similar to the in situ type II pneumocyte and were unchanged by fatty acid supplementation. The phospholipid composition of the cell line was similar to that of primary isolates of type II cells in total phosphatidylcholine, di...
Characteristics KaryotypeThis is a hypotriploid human cell line with the modal chromosome number of 66, occurring in 24% of cells. Cells with 64 (22%), 65, and 67 chromosome counts also occurred at relatively high frequencies; the rate with higher ploidies was low at 0.4%. There were 6 ...
Character- ization of the A549 cell line as a type II pulmonary epithelial cell model for drug metabolism. Exp Cell Res 1998;243:359-366.Foster KA, Oster CG, Mayer MM, Avery ML, Audus KL. Characterization of the A549 cell line as a type II pulmonary epithelial cell model for drug ...
Establishment of a drug sensitivity panel using human lung cancer cell lines. Acta Med. Okayama 53:67-75(1999) PubMed=10536175; DOI=10.3892/ijo.15.5.927 Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J. Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma wit...
Studies have suggested that tumor growth and spread are driven by a minority of cancer cells that exhibit characteristics similar to those of normal stem cells, thus these cells are called cancer stem cells (CSCs). CSCs are believed to play an important role in initiating and promoting cancer....
The pharmacological action of sweet potato extract, cell morphology characteristics, cell cycle distribution, flow cytometry, clinical studies, and plausible medicinal applications of the crop (along with a safety evaluation) require additional research....
Peptides for receptor-mediated imaging and therapy should display at least two characteristics: high bind- ing affinity and antagonism to the tumor. VEGF/VEGFR pathway is mainly responsible for tumor angiogen- esis and growth. Different from VEGF, subsequently blocks the VEGF/VEGFR VsiEgnGaFli1...