Zager RA. Plasma membrane cholesterol: a critical determinant of cel- lular energetics and tubular resistance to attack. Kidney Int 58: 193-205, 2000.Zager RA, Burkhart KM, Johnson ACM, Sacks BM. Plasma mem- brane cholesterol: a critical determinant of cellular energetics and tubular resistance...
Plasma membrane cholesterol regulates human lymphocyte cytotoxic function Cell cholesterol is believed to be confined mainly to the plasma membrane. Treatment here of human peripheral blood lymphocytes with cholesterol-free and c... MP Dabrowski,WE Peel,AER Thomson - 《European Journal of Immunology》...
Cell to cell cohesion in fully keratinized hair is mediated by a cell membrane complex which contains covalently bound (integral) hair lipids. The influence of aging on concentrations of integral cholesterol sulphate (CHSU) and cholesterol (CH) in human scalp hair shafts, and the relationship bet...
Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Pla...
Cholesterol at the Golgi, the levels of which is regulated by oxysterol-binding protein, is essential for the Golgi localization of intra-Golgi v-SNAREs by ensuring proper COP-I vesicle transport34. Caveolin-1, a protein to form caveolae at the plasma membrane, accumulates in the Golgi when ...
Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Pla...
Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich lipoproteins J. Lipid Res., 34 (1993), pp. 1555-1564 View PDFView articleGoogle Scholar 39 C.E. MacPhee, R.Y.S. Chan, W.H. Sawyer, W.F. Stafford, G.J. Howlett Interaction of lipoprotein lipase...
In addition to apolipoproteins, HDL contains an additional protein in the form of the enzyme lecithin:cholesterol acyltransferase (LCAT), which esterifies cholesterol esters by transferring an LCFA moiety from phosphatidylcholine (lecithin) to cholesterol. LCAT is activated by lipoprotein A-I. C Diges...
The pathogenic event common to all forms of Alzheimer's disease is the abnormal accumulation of the amyloid β-peptide (Aβ). Here we provide strong evidence that intracellular cholesterol compartmentation modulates the generation of Aβ. Using genetic,
Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Pla...