2007. Changes in cholesterol levels in the plasma membrane modulate cell signaling and regulate cell adhesion and migration on fibronectin. Cell Motil Cytoskeleton 64:199-216.Ramprasad OG, Srinivas G, Rao KS, Joshi P, Thiery JP, Dufour S et al. Changes in cholesterol levels in the plasma ...
At room temperature, cholesterol functions in the plasma membrane toA.increase fluidity of the lipid bilayer.B.decrease fluidity of the lipid bilayer.C.facilitate the diffusion of ions through the lipid bilayer.D.assist in the transport of hormones acros
The composition of the plasma membrane of malignant cells is thought to influence the cellular uptake of cisplatin and to take part in developing resistance to this widespread anti-cancer drug. In this work we study the permeation of cisplatin through the model membranes of normal and cancer cells...
Covalently modified oxidase electrodes were used to detect cholesterol in the plasma membrane of oocytes and in the macrophage plasma membrane at 37 °C. Also reported are tapping mode – scanning force microscopy of cholesterol oxidase immobilized in a lipid membrane on mica. Topographic and phase ...
L. et al. Hemagglutinin Clusters in the Plasma Membrane Are Not Enriched with Cholesterol and Sphingolipids. Biophys J 108, 1652–1659, doi: 10.1016/J.Bpj.2015.02.026 (2015). 20. Lawrence, J. C., Saslowsky, D. E., Edwardson, J. M. & Henderson, R. M. Real-time analysis of ...
Question 3:Predict what will happen to the plasma membrane if there is no cholesterol. 相关知识点: 试题来源: 解析 Without cholesterol, the plasma membrane will become too fluid at normal bodytemperature and may rupture. Without cholesterol, the membrane will become toopermeable to dissolved ...
We present evidence that 7-ketocholesterol (7KC) is incorporated into the plasma membranes of endothelial cells in excised porcine aortas in molar amounts comparable to the native cholesterol present in the membrane. Our experimental findings indicate that simple adsorption of 7KC does not play a...
Given that the fractional difference in their areas is of the order of the thickness of the plasma membrane to the size of a cell, a fractional difference on the order of 10−3, this is reasonable. In this ensemble, as one cholesterol molecule flips from the outer to the inner leaf, ...
Cholesterol is a primary component of the mammalian cell plasma membrane. Although its function is unknown, it may be of major importance in maintaining membrane fluidity and rigidity 1 . In artificial membrane systems, the addition of cholesterol results in a condensing effect—thickening the bilayer...
The advantage of the CV model is that isolated vesicles remain fusion competent in vitro. CV have comparable Ca2 + sensitivity, fusion kinetics, and molecular composition to other secretory vesicles [26], [29], [30] and CV–CV and CV–plasma membrane fusion, proceed through a common ...