Biochemistry: Painting a picture of protein interactionThe binding interface of interacting proteins is revealed by a novel 'protein painting' technique.doi:10.1038/nmeth.3130TodorovicVesnaNature Methods
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ETR1 (ethylene response 1), GCN2 (general control non-repressible 2), HSF (heat shock factor), ICE (inducer of CBF expression), MAPK (mitogen-activated protein kinase), LHY (late elongated hypocotyl), PA (phosphatidic acid), PP2C (protein phosphatase 2C), PRR (pseudo response regulator),...
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Water is present in the protein core up to a late stage of folding, lubricating conformational transitions during the search process. Once 80% of the native contacts have formed, water is squeezed from the protein interior and the structure descends into the native manifold. Examination of the ...
Protein glycosylation has long been known as a heterogeneous posttranslational modification (PTM) that increases protein diversity and exerts a profound effect on various biological processes1,2,3,4. In spite of some issues remaining unsolved5, great strides have been made in the identification of ...
Without a systematic picture of the physical interactions that link immune cells, any efforts at present to generate truly systems-level views of immune function will remain patchwork at best. Building a surface protein interactome To enable a systematic survey of the surface protein interactions ...
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