Dhingra et al., " A phase-I clinical study of low-dose oral interferon-alpha, " J. Immunother., 14(1):51-55, 1993.DHINGRA, K., DUVIC, M., HYMES, S., McLAUGHLIN, P., ROTHBERG, J., and GUTTERMAN, J.U. (1993). A phase I clin- ical study of low-dose oral interfero...
Dahut, A phase I clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer, J. Urol. 183 (6) (2010) 2219-2226.Figg WD, Woo S, Zhu W, Chen X, Ajiboye AS, Steinberg SM, Price DK, Wright JJ, Parnes HL, Arlen PM, Gulley JL, ...
Clinical phase I study on NC-6004 R Plummer et al 594 CH3O-(CH2CH2O)n-CH2CH2CH2-NH-(CO-CH-NH)m-x-(CO-CH-NH)x-H PEG-pGlu CH2 CH2 C OO CH2 CH2 C O O NH3 Pt NH3 Cisplatin residue Figure 1 Structure of cisplatin-PEG-poly(glutamic acid) block co-polymer conjugate. PEG-pGlu,...
WASHINGTON, June 2 (Xinhua) -- Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers, has been shown to be safe in a Phase I clinical trial, resulting in durable remissions, according to a study published on Saturday in the New England Journal of Medicine...
A Phase I clinical study for pharmacokinetics, safety, tolerance and immunogenicity of QX002N in healthy volunteers: a single-center, randomized, double-blind, single-dose eescalation, placebo-controlled study,Jiangsu Qyuns Therapeutics Co., Ltd,Interven
A phase I clinical and pharmacological study of weekly intravenous infusions of piritrexim (BW301U) 来自 NCBI 喜欢 0 阅读量: 25 作者: GR Weiss,GA Sarosy,TD Shenkenberg,T Williams,NJ Clendeninn,DD Von Hoff,JL Woolley,SHT Liao,M Robert Blum 展开 摘要: Thirty-eight patients with advanced ...
A phase II study of personalized peptide vaccination combined with gemcitabine for non-resectable pancreatic cancer patients We evaluated the safety of, and clinical and immune responses to personalized peptide vaccination with gemcitabine (GEM) as the first line therapy in patie... Noguchi - 《Oncol...
1Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle WA, USA 翻译:付星 摘要 从1941年Huggins和Hodges提出前列腺癌是雄激素依赖的重要认识以来,抗雄激素治疗(androgen deprivation therapy, ADT)一直是转移性...
The fate of camptothecin glycoconjugate: report of a clini- cal hold during a phase II study of BAY 56- 3722 (formerly BAY 38-3441), in patients ... SH Gelderblom - 《Investigational New Drugs》 被引量: 1发表: 2012年 The fate of camptothecin glycoconjugate: report of a clinical hold du...
Clinical trial - WikipediaIIa进行概念验证、IIb进行剂量探索的的有以下来源(这种最常见): Phase IIa Studies (Proof-of-Concept) A Phase IIa study designed to evaluateclinicalconcept is a study that is further on in the early development value chain; it serves to provide a more 'definitive' read ...