The vaccinations produced against nCoV are split into four types: whole virus, protein subunit, viral vector, and nucleic acid (RNA and DNA) vaccines. Some try to inject the antigen into the circulation, while others, like the messenger RNA (mRNA) vaccination, employ the body's cells to ...
The advantages for vaccines range from the acceleration of immunogen discovery to rapid response and multiple disease target manufacturing. A greater understanding of quality attributes that dictate translation efficiency, as well as a comprehensive appreciation of the importance of mRNA delivery, are ...
mRNA technologies have the potential to transform areas of medicine, including the prophylaxis of infectious diseases. The advantages for vaccines range from the acceleration of immunogen discovery to rapid response and multiple disease target manufactur
By the spring of 2021, in the United States and Canada, two mRNA vaccines, as well as one or two adenovirus-vectored vaccines, respectively, have been approved for emergency use (https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines). However, it is ...
Effectiveness of mRNA vaccines and waning of protection against SARS-CoV-2 infection and severe COVID-19 during predominant circulation of the Delta variant in Italy: retrospective cohort study. BMJ. 2022;376:e069052. doi:10.1136/bmj-2021-069052 PubMedGoogle ScholarCrossref 23. Fabiani ...
Cancer vaccines mainly include DNA, mRNA, peptide, protein, DCs, and tumor cell vaccines [68]. In 2010, the first cancer vaccine, sipuleucel-T (DC vaccine), gained approval from FDA to treat prostate cancer as a result of its capacity to prolong overall survival (OS) [69]. Among recentl...
comprehensive perception of immune system schemes, especially those related to the innate immune system immediately after infection, when confronting influenza virus may help to develop more efficient vaccines or improved anti-infection immunotherapies, resulting in a decline in the threat of influenza infe...
Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are still largely unknown. In th
Ferdinands, J.M.; Rao, S.; Dixon, B.E.; Mitchell, P.K.; DeSilva, M.B.; Irving, S.A.; Lewis, N.; Natarajan, K.; Stenehjem, E.; Grannis, S.J.; et al. Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19-Associated Emergency Department and Urgent Care...
For the purpose of this review, articles were identified using the PubMed database through a comprehensive search conducted by combining key terms such as “pollution”, “vaccines”, “inflammation”. English language articles were screened for relevance. In Table 1, a summary of the different ...