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mRNA are snippets of genetic code that instructs cells to produce proteins. mRNA COVID-19 therapies “deliver genetic instructions into your cells,” thereby triggering your body to produce a fragment of the virus (the spike protein). So, mRNA vaccines ARE gene therapy. There’s simply no wa...
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological preparations developed using this platform. During the pandemic, their administration has been proven to be a life‐saving intervention. Here, we review the main advantages of using mRNA vaccines, identify further ...
Jessica Hamzelou wrote about their potential in January, and I followed up with a story after two mRNA researchers won a Nobel Prize. Using self-amplifying RNA isn’t the only way to make mRNA vaccines more powerful. Researchers are tweaking them in other ways that might help boost the...
mRNA technologies have the potential to transform areas of medicine, including the prophylaxis of infectious diseases. The advantages for vaccines range from the acceleration of immunogen discovery to rapid response and multiple disease target manufactur
Assuming that mRNA vaccines will be proven clinically efficacious and safe, one of the central advantages hinges on rapidity of manufacture. Within weeks, clinical batches can be generated after the availability of a sequence encoding the immunogen. The process is cell-free and scalable. Of paramoun...
“New vaccine technologies will likely lead to new types of vaccine harms. Since there has never been an approved mRNA vaccine, we really don’t know what such damage will look like. Because vaccines have been developed so quickly and clinical trials are so short, the long-term damage is ...
Earlier this year, Merriam-Webster added to its online entry for “vaccine” to cover all the talk of mRNA vaccines, or messenger vaccines such as those for COVID-19 developed by Pfizer-BioNTech and Moderna. 今年早些时候,韦氏词典在其在线词条中增加了“vaccine”(疫苗)一词,以涵盖所有关于mRNA疫...
《经济学人》:“The lack of effective vaccines on the Mainland – nationalism precludes Beijing from approving effective western mRNA vaccines – and a vast population with no experience of Covid-19 create a diabolical conundrum.” 翻译:大陆缺乏有效的疫苗——nationalism使Peking无法批准西方有效的mRNA疫...
Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough. By Elie Dolgin Twitter Facebook Email In late 1987, Robert Malone performed a landmark experiment. He mixed strands of messenger RNA with droplets of fat, to create a kind of ...