(2)抑制复杂的嘌呤间的相互转变,即能抑制次黄嘌呤核苷酸转为腺 嘌呤核苷酸及次黄嘌呤核苷酸转为黄嘌呤核苷酸、鸟嘌呤核苷酸的过程,同时本 品还抑制辅酶I(NAD+)的合成,并减少了生物合成DNA所必需的脱氧三磷酸腺苷(dATP)及脱氧三磷酸鸟苷(dGTP),因而肿瘤细胞不能增殖,本品对处于S 增殖周期的细胞较敏感,除能抑制...
6-Thio-dGTP 推荐供应商 建议您优先选择企业会员,我们对企业会员产品有严格审核。 公司名称: BOC Sciences 推荐 投诉 收藏 联系电话: 16314854226 电子邮件: inquiry@bocsci.com 国籍: 美国 产品介绍: 英文名称:6-Thio-dGTP纯度:95% by HPLC CB指数: 58 网址: www.chemicalbook.com/showsupplierproductslist...
额外在反应体系中加入一定量镁离子和聚乙二醇（PEG），并且使用Bst 2.0 DNA聚合酶且在较低的延伸温度下时，6mA不能顺利和2-thio-dTTP进行配对，而同时会和dATP、dGTP、dCTP发生不同比例的错配。
6-Thio-2-Deoxyguanosine-5-Triphosphate (6SdGTP) was employed as a substrate replacing dGTP in sequencing reactions with Sequenase and Thermo Sequenase.doi:10.1080/07328319708006268McDougall, Mark G.McArdle, Bernie F.Kumar, ShivFuller, Carl W....
它能够抑制酰胺转移酶,从而干扰嘌呤核苷酸合成;能够抑制次黄嘌呤核苷酸转为腺嘌呤核苷酸及次黄嘌呤核苷酸转为黄嘌呤核苷酸、鸟嘌呤核苷酸的过程;还能够抑制烟酰胺腺嘌呤二核苷酸(NAD+)的合成及引起脱氧腺苷三磷酸(dATP)和脱氧鸟苷三磷酸(dGTP)水平的下降。这使得巯嘌呤能够有效抑制DNA的合成,从而抑制肿瘤细胞的生长。
To be cytotoxic, 6-TG must be converted into the thioguanylic nucleotide. The efficiency of this conversion is due to a balance between the activity of the enzymes responsible for its conversion to the phosphorylated derivatives and of those responsible for the transformation of the base analog ...
SCAM-120423 6-Thio-dGTP N/A SCAM-120426 6-Thio-GpCp N/A SCAM-120430 6-Thio-GppCp N/A SCAM-120434 6-Thio-GppNHp N/A SCAM-120437 6-Methylthio-GMP N/A SCAM-120444 6-Methylthio-GDP N/A SCAM-120448 6-Methylthio-GTP 70318-62-6 SCAM-120451 6-Methylthio-IMP 7021-52-5 SC...
SCAM-122033 γ-(6-Aminohexyl)-ATP-ATTO-Thio12 N/A SCAM-122036 γ-(6-Aminohexyl)-ATP-ATTO-Rho12 N/A SCAM-122037 γ-(6-Aminohexyl)-ATP-DY-776 N/A SCAM-122038 γ-(6-Aminohexyl)-ATP-6-ROX N/A SCAM-122041 γ-(6-Aminohexyl)-ATP-DY-751 N/A SCAM-122042 γ-(6-Aminohexyl)...
Isopropyl-1-thio-β-d-galactopyranoside (1 mm) was added to the culture at A600 nm ∼ 0.4, and 4 h later, the cells were harvested and washed with TM buffer. The yield was approximately 3.7 g of wet weight of cells/liter. Electrophoresis Procedures The Novex X-Cell mini system (...
In a similar manner, dTTP stimulates GDP reduction and dGTP stimulates ADP reduction. By having this regulation, the enzyme ensures that there will be a balanced supply of all four dNTPs in the cell. The mechanism behind the specificity site function is known from experiments where the R1 ...