因此,研究5-HT及其受体的功能与认知记忆的关系可能为研发潜在的神经退行性疾病的治疗策略提供启示。 在之前的一项工作中,贝勒医学院徐勇教授团队发现了一种罕见的5-HT2C受体(由基因HTR-2C基因编码)的loss-of-function突变会导致肥胖[1],且临床上这些患者出现了不同程度的认知障碍。那5-HT及其受体是如何影响认知与...
and (ii) what are the effects of systemic infection, modelled by systemic injection of the bacterial endotoxin LPS, on 5-HT function in the rat brain?Raley, JDavis, ASharp, TAnthony, DSibson, N
5.Carhart-Harris, R.L. and D.J. Nutt, Serotonin and brain function: a tale of two receptors. J Psychopharmacol, 2017. 31(9): p. 1091-1120.
2022年12月19日，贝勒医学院徐勇课题组与剑桥大学Sadaf Farooqi课题组合作在Nature Medicine上发表题为 Human loss-of-function variants in the Serotonin 2C receptor associated with obesity and maladaptive behavior 的研究论文，首次发现5-HT2CR参与调节人类的食欲、体重和行为。首先， 研究人员通过对2548名（46%...
products.forEach(function(product){ var data = new ht.Data(); data.a(product); listView.dm().add(data); }); 数据的添加是不是很简单,但是ListView组件上显示的内容默认是Data的name属性或displayName属性,在创建Data时,并没有对Data设置displayName或者name属性,所以这个时候在页面上看到的还是一个空的...
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2022年12月19日,贝勒医学院徐勇课题组与剑桥大学Sadaf Farooqi课题组合作在Nature Medicine上发表题为Human loss-of-function variants in the Serotonin 2C receptor associated with obesity and maladaptive behavior的研究论文,首次发现5-HT2C...
If the inclusion has a finite shear modulus, the angular dependency of the stresses is the same whether or not there exists a shear stress 蟽 within the interval containing the dislocations, but the actual values of the local stresses, which are a power function of the distance from the ...
Ziegelstein RC ,Parakh K ,Sakhuja A ,et a1.Platelet function in patients with major depression[ J] .Internal Medicine Journal , 2009 ,1( 39) :38 —43 13 Shimbo D ,Child J ,Davidson K ,et a1.Ex aggerated serotonin — med iated platelet reactivity as a possible link in depression an...
In conclusion, the 5-HT, receptors in the CeA of rats mediate the modulation of thymus function, at least partly, through the neuroendocrine circuit of the limbic system-cortex-hypothalamus-PAG. 展开 关键词: 5-HT3 receptor 1-phenylbiguanide central amygdala thymocyte c-Fos neuroimmunomodulation ...