1996. 5-Azacyti- dine treatment induces autoimmune vitiligo in the parental control strains of the Smyth line chicken model for autoim- mune vitiligo. Clin. Immun. Immunopathol. 81:136-144.azacytidine treatment induces autoimmune vitiligo in parental control strains of the Smyth line chicken model...
8、Constantinides, P. G., Jones, P. A. & Gevers, W. Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature267, 364-366, doi:10.1038/267364a0 (1977). 9、Cimmino, L. et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukem...
7、Lyko, F. The DNA methyltransferase family: a versatile toolkit for epigenetic regulation.Nat Rev Genet19, 81-92, doi:10.1038/nrg.2017.80 (2018). 8、Constantinides, P. G., Jones, P. A. & Gevers, W. Functional striated muscle cells from non-myoblast precursors following 5-azacytidine tr...
5-azacytidine and arabinosyl adenine for the treatment of acute leukemiaALL acute lymphoid leukemiaacute lymphoid leukemiaAML acute myeloid leukemiaacute myeloid leukemiaAra-A arabinosyl adeninearabinosyl adenineAra-C arabinosyl cytosinearabinosyl cytosine...
在一项1期临床试验中,已经发现口服5-阿扎胞苷(5-azacytidine, AZA)和罗米地新(romidepsin, ROMI)是安全有效的,在复发/难治性(relapsed/refractory, R/R)PTCL患者中具有谱系选择性活性。入组的初治(treatment-naïve, TN)或R/R PTCL患...
英文名称Azacitidine (5-Azacytidine) CAS320-67-2 分子式C8H12N4O5 分子量244.2 储存条件RT 纯度≥98.0% 外观(性状)白色粉末 单位支 原理: 科研试剂,广泛应用于分子生物学,药理学等科研方面。5-氮杂胞嘧啶核苷为一种低甲基化的强效生长抑制剂及细胞毒素剂,抑制 DNA 甲基转移酶 。也是作用于S期的细胞周期特异...
为深入了解慢性粒细胞性白血病(CML)领域的最新研究成果,《肿瘤瞭望-血液时讯》特邀四川大学华西医院朱焕玲教授进行深度解读。 摘要号:S170 泊那替尼和阿扎胞苷治疗慢粒急髓变PONAZA试验 (NCT03895671)结果报告PONATINIB AND 5-AZACYTIDINE FOR ...
The RE lines are significantly hypomethylated relative to their progenitor [22] and may be referred to as ‘epimutant’ lines, however, it cannot be ruled out that the cause of the early-flowering phenotype is the result of a genetic mutation that occurred during the 5-azacytidine treatment. ...
5-azacytidine treatment reorganizes genomic histone modification patterns. Epigenetics 2010; 5: 229–240. 41 Bogenberger JM, Shi C-X, Gonzales I, Tiedemann R, Noel P, Slack J et al. RNAi screening identifies BCL-XL as an erythroid lineage-specific 5-Azacytidine sensitizer while the BCL-2/...
^Cihák A (1974). "Biological effects of 5-azacytidine in eukaryotes".Oncology30(5): 405–22. PMID 4142650. ^Whitelaw E and Garrick D (2005),The Epigenome,Chapter 7,In:Mammalian Genomics, Ed: Ruvinsky A & Marshall Graves JA, CABI Publishing, Wallingford, UK,ISBN 0851999107. ...