4T1 小鼠乳腺癌细..细胞介绍4T1 是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当注射到BALB/c 小鼠中时,4T1自发产生高转移肿瘤,可转移到肺,肝,淋巴结和大脑,同时在注射部位形成始发灶。诱导转移时不
Mouse Breast Cancer Cells ,4T1 细胞介绍: 4T1 是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当注射到BALB/c 小鼠中时,4T1自发产生高转移肿瘤,可转移到肺,肝,淋巴结和大脑,同时在注射部位形成始发灶。诱导转移时不需要摘除始发灶。4T1细胞在BALB/c小鼠中的生长与转移特性与人体中的乳腺癌十分相近...
Pulaski, B.A. and S. Ostrand-Rosenberg, Mouse 4T1 breast tumor model. Curr Protoc Immunol, 2001.Chapter 20: p. Unit 20.2. Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016. Walker, I., et al., Mammary tumors induce central pro-inflammatory cytokin...
4T1细胞在BALB/c小鼠中的生长与转移特性与人体中的乳腺癌十分相近。这种肿瘤是人VI期乳腺癌的动物模型。4T1-诱导的肿瘤在手术后及未手术情况下转移的动力学相近,可以用作手术后及未手术模型。 跟其他肿瘤模型相比,由于4T1的抗6-硫鸟嘌噙特性,微小的转移细胞团(少到仅仅1个)也可以在许多远端器官中检测到。该...
Pulaski, B.A. and S. Ostrand-Rosenberg, Mouse 4T1 breast tumor model. Curr Protoc Immunol, 2001. Chapter 20: p. Unit 20.2.Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016.Walker, I., et al., Mammary tumors induce central pro-inflammatory ...
[1] Pulaski BA, Clements VK, Pipeling MR, Ostrand-Rosenberg S. Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon gamma. Cancer Immunol Immunother. 2000 Apr;...
with major histocompatibility complex class II and B7.1 cell-based tumor vaccines. Cancer Res. ...
Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon gamma. Cancer Immunol Immunother. 2000 Apr;49(1):34-45. [2] Pulaski BA, Ostrand-Rosenberg S. Reduction ...
Mouse Breast Cancer Cells 4T1-A;小鼠乳腺癌细胞 来源ATCC 传代方法1:2至1:3,每周 3次 种属小鼠 组织来源乳房 生长特性贴壁生长 细胞形态上皮细胞样 背景介绍4T1是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当注射到BALB/c 小鼠中时,4T1自发产生高转移肿瘤,可转移到肺,肝,淋巴结和大脑,同时在...
Pulaski, B.A. and S. Ostrand-Rosenberg, Mouse 4T1 breast tumor model. Curr Protoc Immunol, 2001.Chapter 20: p. Unit 20.2. Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016. Walker, I., et al., Mammary tumors induce central pro-inflammatory cytokin...