4T1细胞在BALB/c小鼠中的生长与转移特性与人体中的乳腺癌十分相近。这种肿瘤是人VI期乳腺癌的动物模型。4T1-诱导的肿瘤在手术后及未手术情况下转移的动力学相近,可以用作手术后及未手术模型。 跟其他肿瘤模型相比,由于4T1的抗6-硫鸟嘌噙特性,微小的转移细胞团(少到仅仅1个)也可以在许多远端器官中检测到。
Mouse Breast Cancer Cells ,4T1 细胞介绍: 4T1 是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当注射到BALB/c 小鼠中时,4T1自发产生高转移肿瘤,可转移到肺,肝,淋巴结和大脑,同时在注射部位形成始发灶。诱导转移时不需要摘除始发灶。4T1细胞在BALB/c小鼠中的生长与转移特性与人体中的乳腺癌十分相近...
参考文献 Pulaski, B.A. and S. Ostrand-Rosenberg, Mouse 4T1 breast tumor model. Curr Protoc Immunol, 2001.Chapter 20: p. Unit 20.2. Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016. Walker, I., et al., Mammary tumors induce central pro-inflammato...
2001. Chapter 20: p. Unit 20.2.Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016.Walker, I., et al., Mammary tumors induce central pro-inflammatory cytokine expression, but not behavioral deficits in Balb/C mice. Scientific Reports, 2017. 7(...
Maxwell, K.G., Immunomodulation of Breast Cancer Cells for Whole Tumor Vaccination. 2016. Walker, I., et al., Mammary tumors induce central pro-inflammatory cytokine expression, but not behavioral deficits in Balb/C mice. Scientific Reports, 2017.7(1): p. 1-13. ...
规格1×10⁶cells/T25培养瓶 品 牌圣尔生物share-bio 一键复制产品信息 产品编号名称包装品牌目录价促销价货期数量购物车 SB-MU21254T1 (小鼠乳腺癌细胞系) (STR鉴定正确) 4T1 (mouse breast cancer cell) (STR identification correct)1×10⁶cells/T25培养瓶圣尔生物share-bio¥699.00 ...
参考文献 [1] Pulaski BA, Clements VK, Pipeling MR, Ostrand-Rosenberg S. Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon gamma. Cancer Immunol Immunother. ...
Due to the heterogeneity of breast cancer cells, cytotoxic treatments targeting proliferative cancer cells could not eradicate all cancer cells. Compelling evidence suggests that breast cancer stem cells (BCSCs) have a crucial impact in current shortcomings of cancer therapy because they are largely ...
4T1小鼠乳腺癌细胞(种属鉴定正确) Mouse Breast Cancer Cells4T1-A;小鼠乳腺癌细胞 来源 ATCC 传代方法 1:2至1:3,每周 3次 种属 小鼠 组织来源 乳房 生长特性 贴壁生长 细胞形态 上皮细胞样 背景介绍 4T1是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当注射到BALB/c 小鼠中时,4T1自发产生...
MR, Ostrand-Rosenberg S. Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells ...