Structure and dynamics of 30-nm chromatin fiber in gene regulation在高等生物个体的发育和生长过程中,细胞通过调控细胞核内染色质高级结构的动态变化来有选择性地进行基因的激活和沉默,从而控制细胞自我维持或定向分化,决定细胞的组织特异性和细胞命运.染色质结构的高度动态变化在基因转录沉默和激活过程中起重要作用,...
ChIP-00110×交联终止剂48 mL+4 °C ChIP-002Chromatin Extract Buffer24 mL+4 °C ChIP-005ChIP W...
Detection and iden- folding for the 30-nm chromatin fiber. Nat Struct Mol tification of single molecules in living cells using spec- Biol, 2009, 16: 534-540 trally resolved fluorescence lifetime imaging microscopy. [13] Song F, Chen P, Sun D P, et al. Cryo-EM study of the Anal...
Adkins, N.L., M. Watts, and P. T. Georgel. 2004. To the 30-nm chromatin fiber and beyond. Biochim. Biophys. Acta. 1677:12-23.Adkins, N.L., M. Watts, and P.T. Georgel, To the 30-nm chromatin fiber and beyond. Biochim Biophys Acta, 2004. 1677(1-3): p. 12-23....
30nm染色质纤维的结构及调控*梁丹陈萍李国红**(中国科学院生物物理研究所,生物大分子国家重点实验室,北京100101)摘要真核细胞中,基因组DNA缠绕组蛋白八聚..
We demonstrated that the chromosome consisted of chromatin fibres of an average diameter of 16.9-nm. The majority of the chromatin fibres had diameters between 5 and 25-nm, while those with 30-nm were in the minority. The reduced packaging ratio of the chromatin fibres was detected at axial ...
About a decade ago, the elastic properties of a single chromatin fiber and, subsequently, those of a single nucleosome started to be explored using optical and magnetic tweezers. These techniques have allowed direct measurements of several essential physical parameters of individual nucleosomes and nucl...
chromatin domain3D genome organizationSeveral hierarchical levels of DNA packaging are believed to exist in chromatin, starting from a 10-nm chromatin fiber that is further packed into a 30-nm fiber. Transitions between the 30-nm and 10-nm fibers are thought to be essential for the control of...
Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber. Nat. Struct. Mol. Biol. 16:534-540.Kruithof M, Chien FT, Routh A, Logie C, Rhodes D, van Noort J. Single-molecule force spectroscopy reveals a highly compliant helical folding for ...
G. (2008) Topological constraints on the possible structures of the 30-nm chromatin fiber . Chromosoma 117 , 67–76D.Z. Staynov, Y.G. Proykova, Topological constraints on the possible structures of the 30 nm chromatin fibre, Chromosoma 117 (2007) 67-76....