Branched-chain DSF-family signalsPathogenesisThe 3-ketoacyl-ACP synthase III (FabH), a key enzyme for bacteria growth, catalyses the last step of the initiation of bacterial fatty acid synthesis. Rice bacterial blight is caused by the pathogenXanthomonas oryzaepv.oryzae(Xoo), which is widely ...
专利名称：3-ketoacyl-ACP-reductase (FabG) of Staphylococcus aureus 发明人：Jianzhong Huang,Damien McDevitt 申请号：US09/238481 申请日：19990128 公开号：US06110704A 公开日：20000829 专利内容由知识产权出版社提供 摘要：The invention provides fabG polypeptides and polynucleotides encoding fabG polypeptides ...
Selection of an Escherichia coli host that expresses mutant forms of Mycobacterium tuberculosis 2-trans enoyl-ACP(CoA) reductase and 3-ketoacyl-ACP(CoA) re... Tuberculosis (TB) still remains a worldwide health concern. Efforts to understand the complex biology of Mycobacterium tuberculosis, the ...
ketoacyl-thioesters are unstable, the reactions contained the purifiedE. colifatty-acid synthetic enzymes; 3-ketoacyl-ACP reductase (FabG), 3-hydroxyacyl ACP dehydratase (FabA), and enoyl-ACP reductase (FabI) and NADH to convert the condensation product to the stable fully saturated form. By u...
Provided are non-natural or variant beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS) II enzymes (KASII), polynucleotides encoding such variant KASII, host cells expressing such variant KASII, oils and oil products produced by such cells, and methods of making and using such variant KA...
Hakozaki H, Park JI, Endo M, Takada Y, Kaazama T, Takeda Y, Suzuki G, Kawagishi-Kobayashi M, Watanabe M (2008) Expression and developmental function of the 3-ketoacyl-ACP synthase2 gene in Arabidopsis thaliana. Genes and Genet Syst 83: 143-152...
The invention provides fabG polypeptides and polynucleotides encoding fabG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabG polypeptides to screen for antibacterial compounds.JIANZHONG HUANGDAMIEN MCDEVITT...
KAS IV: a 3-ketoacyl-ACP synthase from Cuphea sp. is a medium chain specific condensing enzyme. Dehesh K,Edwards P,Fillatti J,Slabaugh M,Byrne J. Plant Journal The . 1998Dehesh, K. , Edwards, P. , Fillatti, J. , Slabaugh, M. and Byrne, J. ( 1998 ) KAS IV: a 3-ketoacyl-...
FabG catalyzes the essential 3-ketoacyl-ACP reduction step in the FAS II fatty acid synthesis pathway. Site-directed mutagenesis studies of several other SDR enzymes has identified three highly conserved amino acid residues, Ser, Tyr, and Lys, as the catalytic triad. Structural analyses of E. ...
Nucleic acids encoding 3-ketoacyl-ACP reductase from Moraxella catarrahalisThe present invention provides the genomic sequences of a library of purified nucleic acid molecules, or their complements, comprising the genome of proteins or portions thereof.KIM L. BERG...