d-2-Hydroxyglutarate 是一种抗炎免疫代谢物,在 TLR4 激活后的巨噬细胞中积累 Chestnut Studying 摘要 Macrophages undergo extensive metabolic rewiring upon activation which assist the cell in roles beyond energy production and synthesis of anabolic building blocks. So-called immunometabolites that accumulate...
Disodium (R)-2-Hydroxyglutarate 价格电议 起批量≥1 支 最小起订1支 供货总量1000支 发货地址湖北省武汉市 建议售价￥100/支 更新日期2025年01月17日 产品规格20mg 即时洽谈立即询价查看联系方式 收藏产品发送留言 VIP6年 武汉科斯坦生物科技有限公司 ...
D-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric) 供应商 Biovision 产品货号 K213-100 产品报价 ￥询价/100assays 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868. 产品新闻
(R)-2-Hydroxyglutarate 更新日期:2024-10-28 上海捷世凯生物科技有限公司 联系人:方瑞 手机:15221441005 QQ:2413644182 联系电话:15221441005 在线询单QQ交流电话询单 产品编号品牌纯度规格库存价格 D937575麦克林≥98%5mg现货1,620.00 元 公司信息 产品详情...
Mutations in isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) have been shown to be present in most World Health Organization grade 2 and grade 3 gliomas in adults. These mutations are associated with the accumulation of 2-hydroxyglutarate (2HG) in the tumor. Here we report the noninvasive...
2-hydroxyglutarate DNA repair lineage fidelity epigenome fluctuation cancer cell plasticity luminal-to-basal transition single-cell epigenomics chromatin CyTOF Introduction Breast cancer is characterized by prominent cell-to-cell variations in molecular makeup, and enhanced heterogeneity predisposes affected indiv...
Synthesis of 1-octyl-D-2-hydroxyglutarate was performed as previously described38. Briefly, commercialR(-)-tetrahydro-5-oxofuran-2-carboxylic acid (910 mg, 7 mmol) was dissolved in water (1 ml), cooled to 0 °C and treated with 1 N KOH (14.7 ml, 14.7 mmol). After...
The oncometabolite (R)-2-hydroxyglutarate (R-2-HG) produced by isocitrate dehydrogenase (IDH) mutations promotes gliomagenesis via DNA and histone methylation. Here, we identify an additional activity of R-2-HG: tumor cell–derived R-2-HG is taken up by T cells where it induces a perturbati...
(R)-2-Hydroxyglutarate,≥98% (R)-2-Hydroxypentanedioic acid ; 别名: ; 产品编号:M94333 ; CAS:13095-47-1; 分子式:C5H8O5 ; MDL: ; 品牌: 迈瑞尔 ; 货号 品牌 包装 库存 市场价 促销价 数量 购物车 M94333-10MG 迈瑞尔 10mg 华东(现货*) ￥2900 ￥2320.0 - + M94333-25MG 迈瑞尔 25mg...
Mutations of isocitrate dehydrogenases 1 and 2 (IDH1/2) frequently occur in gliomas, which leads to accumulation of oncometabolic product 2-hydroxyglutarate (2HG). Moreover, IDH1/2 mutations were found to correlate with better prognosis in glioma patients. In the present study, we investigated ...