2′‐O‐methyl‐RNA (2′‐O‐Me‐RNA)doi:10.1002/9783527678679.dg13963This article has no abstract.Wiley‐VCH Verlag GmbH & Co. KGaAThe Dictionary of Genomics, Transcriptomics and Proteomics
The stability of hybrids of 2'-O-methyl-ribonucleotides with complementary RNA is considerably higher than that of the corresponding DNA.RNA duplexes. The 2'-O-modified ribonucleotides are thus an att... 详情 Effect of PGE2 and of agents that raise cAMP levels on macrophage activation indu...
2’-O-Methylguanosine,RNA modified nucleoside Gm 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one 2'-O-Methylguanosine USP/EP/BP 2'-OMe-rG Guanosine, 2'-O-methyl- 2'-O-MethylguanosineHydrate> 2'-OMe-Gr 2'-O-Methylguanosine...
This modification was extensively studied for decades in rRNAs and tRNAs, but recent data revealed the presence of 2′-O-methyl groups also in low abundant RNAs, like mRNAs. Ribose methylation is formed in RNA by two alternative enzymatic mechanisms: either by stand-alone protein enzymes or by...
Epitranscriptomic modifications of mRNA are important regulators of gene expression. While internal 2′-O-methylation (Nm) has been discovered on mRNA, questions remain about its origin and function in cells and organisms. Here, we show that internal Nm
Freund, N., Taylor, A.I., Arangundy-Franklin, S. et al. A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA. Nat. Chem. (2022). https://doi.or...
大家好,本周为大家分享一篇发表在Anal. Chem.上的文章“Identification of Inosine and 2′‑O‑Methylinosine Modificationsin Yeast Messenger RNA by Liquid Chromatography−Tandem Mass Spectrometry Analysis”。本文的通讯作者是武汉大学...
2'-O-Methyluridine 英文别名: 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxyMethyl)-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;OMe-rU;2'-OMe-Ur;2'-OMe-rU;2'-O-Me-U;2'-OMe-rU;2'-OMe Uridine;2-Methyoxy uridine;2'-O-Methyluridine;2 '- Methoxyuridine ...
LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation Lihui Liu, Ziyang Liu, Qinghua Liu, Wei Wu, Peng Lin, Xing Liu, Yuechuan Zhang, Dongpeng Wang, Briana C. Prager, Ryan C. Gimple, Jichuan Yu, Weixi Zhao, Qiuli...
Mc Closkey课题组在1993年建立了一种LC-ESI-MS方法用于RNA修饰的定位分析, 成功定位了E.coli 23S rRNA中的3-Methylpseudouridine (m3Ψ) , 超嗜热古细菌P.occultum 5S rRNA中的ac4C和N4-acetyl-2’ ;-O-methylcytidine (ac4Cm) , 以及E.coli tmRNA中的5-Methyluridine (m5U) 和Ψ等。为提高检测灵敏度...