Methods: 18F-FEPPA PET/MR Data from nine subjects (3 HAB [high affinity binder], 6 MAB [mixed affinity binder]) diagnosed with neurological long COVID (LC group) and thirteen controls (4 HAB, 9 MAB) scanned before the COVID-19 outbreak (CTL group) were included in this study. All ...
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Expression of translocator protein (TSPO) on the outer mitochondrial membrane of activated microglia is strongly associated with neuroinflammation. The second-generation PET ligand [18F]FEPPA specifically binds TSPO to enable in vivo visualization and qu
www.nature.com/scientificreports OPEN received: 14 February 2016 accepted: 13 July 2016 Published: 22 August 2016 Monitoring Tumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling after Photodynamic Therapy Xiao Tong1,2, Avinash Srivatsan1, Orit Jacobson1,Yu Wang1, Zhantong ...
MicroPET/CT Imaging of [18F]-FEPPA in the Nonhuman Primate: A Potential Biomarker of Pathogenic Processes Associated with Anesthetic-Induced Neurotoxicity Background. The inhalation anesthetics nitrous oxide (N2O) and isoflurane (ISO) are used in surgical procedures for human infants. Injury to the...
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molecules Article [18F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model Nicolas Vignal 1,2, Salvatore Cisternino 2,3, Nathalie Rizzo-Padoin 1,2, Carine San 1 ID , Fortune Hontonnou 4, ...
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