HPGD 官方全称 15-hydroxyprostaglandin dehydrogenase HGNC ID HGNC:5154 别称 15-hydroxyprostaglandin dehydrogenase (NAD(+)), SDR36C1, short chain dehydrogenase / reductase family 36C, member 1 位点类型 gene with protein product 染色体位置 4q34.1 ...
Whereas, overexpression of 15-PGDH in cancer cells causes apoptosis, cell cycle arrest, and inhibition of metastasis, and hence considered as a tumor suppressor. Hypermethylation of CpG islands in the gene promoter region is an important mechanism to silence the expression of 15-PGDH and ...
公开本文所述的一般使用方法的基础教科书包括sambrook和russell,molecular cloning,alaboratory manual(第3版,2001);kriegler,gene transfer and expression:alaboratory manual(1990);以及current protocols in molecular biology(ausubel等人编,1994))。 24.对于核酸,大小以千碱基(kb)、碱基对(bp)或核苷酸(nt)给出。单...
描述:Recombinant Human HPGD is produced by our Mammalian expression system and the target gene encoding Met1-Gln266 is expressed with a 6His tag at the C-terminus. Accession:P15428 中文别名:15-PGDH蛋白; HPGD蛋白 来源:Human Cells 纯度:Greater than 95% as determined by reducing SDS-PAGE. ...
RayBio® Human 15-PGDH/HPGD ELISA Kit for Cell Culture Supernatants. CODE:ELH-15PGDH-1 Number of Plates: Antigen Information Accession Number: P15428 Gene ID: 3248 Gene Symbols: HPGD PGDH1 SDR36C1 Protein Name & Synonyms: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC ...
15-Hydroxyprostaglandin Dehydrogenase Entrez Gene IDs 3248 (Human); 15446 (Mouse); 79242 (Rat) Alternate Names 15-hydroxyprostaglandin dehydrogenase [NAD+]; 15PGDH; 15-PGDH; EC 1.1.1; EC 1.1.1.141; HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrog...
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary ...
Entrez Gene IDs 3248 (Human); 15446 (Mouse); 79242 (Rat) Alternate Names 15-hydroxyprostaglandin dehydrogenase [NAD+]; 15PGDH; 15-PGDH; EC 1.1.1; EC 1.1.1.141; HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH1; PGDH1PGDH; Prostagl...
REFERENCES Brennan JA, Boyle JO, Koch WM (1995) Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 332: 712–717 Breyer RM, Bagdassarian CK, Myers SA, Breyer MD (2001) Prostanoid receptors: subtypes and ...
PCR产物的定性: 取PCR产物2 μL置2.5%琼脂糖凝胶电泳, 用全自动凝胶成像分析系统(美国SYGENE公司)进行拍照, 以15-PGDH/β-actin比值×100分别表示COX-2、15-PGDH mRNA相对表达量. 1.2.2 COX-2、15-PGDH蛋白的表达检测: 从液氮罐中取出各组织剪碎后, 加入细胞裂解液裂解匀浆使其充分裂解(操作在冰上进行);...