MCE 站:15-Deoxy-Δ-12,14-prostaglandin J2 产品活性:15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) 是一种环戊烯酮前列腺素和 PGD2 的代谢产物。15-Deoxy-Δ-12,14-prostaglandin J2 是一种选择性的 PPARγ (EC50 为2 ?M) 和共价的 PPARδ 激动剂。15-Deoxy-Δ-12,14-prostaglandin J2 促进 ...
jjdjmesy@korea.ac.kr Accepted 2 May 2005 Abbreviations: 15d-PGJ2, 15-deoxy-Δ12,14-PGJ2; IL-6R, IL-6 re- ceptor; MAPK, mitogen-activated protein kinase; MNC, mononu- clear cells; PKC, protein kinase C; PPARγ, peroxisome prolifera- tors-activated receptor γ; SOCS, suppressor of...
15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) 是一种环戊烯酮前列腺素和 PGD2 的代谢产物。15-Deoxy-Δ-12,14-prostaglandin J2 是一种选择性的PPARγ(EC50为 2 µM) 和共价的 15-Deoxy-Δ12,14-Prostaglandin J2-d9Chemical Structure *Please selectQuantitybefore adding items. 上海金畔生物科技...
15-Deoxy-Δ-12-14-PGJ2 Regulates Apoptosis Induction and Nuclear Factor-κB Activation Via a Peroxisome Proliferator-Activated Receptor-γ–Independent Mec... The peroxisome proliferator-activated receptor-γ (PPARγ) high-affinity ligand, 15-deoxy-Δ-12,14-PGJ2 (15d-PGJ2), is toxic to m.....
Our results show that p50 is a target for covalent modification by 15d-PGJ2, both in vitro and in intact cells, and that this interaction results in the inhibition of NF-κB binding to DNA. EXPERIMENTAL PROCEDURES Materials 15-Deoxy-Δ12,14-PGJ2 was from Calbiochem-Novabiochem. 15-Deoxy-...
Cyclopentenone prostaglandins (CyPG), such as 15-deoxy- 12,14 -PGJ2 (15d-PGJ2), are arachidonic acid-derived endogenous electrophiles that possess anti-HIV activity by an unknown mechanism. Given that the reactive ,-unsaturated ketone in the cyclopentenone ring of 15d-PGJ2 covalently modifies ...
(PG)D2 and 15-deoxy-D12,14-PGJ2, but not PGE2, mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases F Zhu1, P Wang1, A Kontrogianni-Konstantopoulos2 and K Konstantopoulos*,1 Excessive mechanical loading of cartilage producing hydrostatic ...
英文名称: 15-deoxy-D12,14-PGJ2 Correlate-EIATM Kit 96 Well 英文同义词: 15-deoxy-D12,14-PGJ2 Correlate-EIATM Kit 96 Well CAS号: 分子式: 分子量: 0 EINECS号: Mol文件: Mol File 15-deoxy-D12,14-PGJ2 Correlate-EIATM Kit 96 Well 信息错误报告 提交 按...
15-deoxy-Delta12,14-PGJ2 (15d-PGJ2) has been identified as an endogenous ligand for PPARgamma, inducing adipogenesis in vitro. Additional roles for this molecule in the propagation and resolution of inflammation, ligation of NF-kappaB, and mediation of apoptosis have been proposed. However, qua...