一月一针,MASH新药Ⅱ期公布积极结果! 2024年3月13日,反义寡核苷酸(Antisense Oligonucleotide, ASO)领域的领军企业Ionis Pharmaceutics 公布了ION224在MASH治疗临床试验中的积极结果。根据披露信息,试验达到主要终点,所有试验组NAS评分至少降低2分的比例均有明显改善,且达到关键次要终点。 01 临床数据 此次公布的II期临床...
3.CD44-specific antisense oligonucleotide on pro-liferation and apoptosis of human trabecular meshwork cells;CD44反义寡核苷酸对人眼小梁细胞增生与凋亡的影响 英文短句/例句 1.Combined Anti-cancer Effects of Multiple Antisense Oligodeoxynucleotides;反义寡核苷酸联合用药的抗肿瘤研究 2.Antisense Oligonucleotides:...
本文介绍了使用OligoWorks SPE微孔板试剂盒(以下简称OligoWorks试剂盒)从大鼠血浆中提取脂质偶联反义寡核苷酸(ASO),然后在LC-HRMS系统上进行定量分析的工作流程。OligoWorks试剂盒是一种简单且适用性广的样品前处理解决...
本应用简报展示了Xevo™ TQ Absolute三重四极杆质谱仪对人血浆基质中不同长度(18~33个核苷酸)、连接子和修饰的寡核苷酸进行生物分析的灵敏度和适用性。 左图:搭载Waters ACQUITY Premier UPLC的Waters Xevo TQ Absolute系统; 右图:使用LC-MS/MS IP生物分析方法在4分钟...
Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle; STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响 2. Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice; 反义寡核苷酸和激素干预对哮喘小鼠GATA-3表达的...
1) Antisense oligonucleotide(ASON) 反义寡核苷酸(ASON)2) antisense oligonucleotides 反义寡核苷酸 1. Stduy on inhibition of proferation of lens epithelial cells by Ccnd1 antisense oligonucleotides liposomes in rats; Ccnd1反义寡核苷酸脂质体抑制大鼠晶状体上皮细胞增殖的研究 2. Inhibiting effect of Cc...
1) antisense oligonucleotide 反义寡核苷酸 1. Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle; STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响 2. Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice; ...
1) p53 antisense oligonucleotide p53反义寡核苷酸2) antisense oligonucleotides 反义寡核苷酸 1. Stduy on inhibition of proferation of lens epithelial cells by Ccnd1 antisense oligonucleotides liposomes in rats; Ccnd1反义寡核苷酸脂质体抑制大鼠晶状体上皮细胞增殖的研究 2. Inhibiting effect of Ccnd1 ...
5) antisense oligonucleotide 反义寡核苷酸 1. Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle; STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响 2. Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice; ...
6) antisense oligonucleotide 反义寡核苷酸 1. Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle; STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响 2. Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice; ...