Although there were trends toward a dose response within a dosage range of 20–80 mg twice daily, results were not consistent.Optimum duration of therapy not known, but efficacy maintained for up to 52 weeks in a clinical trial. In patients responding to ziprasidone therapy, continue the drug...
Ziprasidone is a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. The initial evidence suggests an effective dosage range of 80 160 mg/day. Clinical trials suggest that the drug is an effective antipsychotic in schizophrenia and schizoaffective disorder with a ...
placebo-controlled clinical trials. There were trends toward dose response within the range of 20 mg to 80 mg twice daily, but results were not consistent. An increase to a dose greater than 80 mg twice daily is not generally recommended. The safety of doses above 100...
Ziprasidone In pediatric populations, use ofziprasidoneis off-label. Beforeziprasidonetherapy is initiated, a careful history must be obtained to identify possible cardiac contraindications. Baseline ECG and follow up after reaching final dosage are recommended. ...
Age, sex, race, renal or hepatic impairment or smoking status had no clinically significant effects (i.e. those requiring dosage adjustment) on the pharmacokinetic properties of oral ziprasidone.[8] Intramuscular ziprasidone has not been formally evaluated in elderly patients or patients with hepatic...
Dosage and usageThe initial dose is 2 times per day with 20mg each time through oral administration. The bioavailability is usually bioavailability 30% with administration together with food being able to double the absorption of this product, reaching the bioavailability of 60%; administration with ...
Maintenance treatment of bipolar I disorder as an adjunct to lithium or valproate: Continue treatment at the same dose on which the patient was initially stabilized, within the range of 40 to 80 mg twice daily. (2.3) Dosage Forms and Strengths Capsules: 20 mg, 40 mg, 60 mg, and 80 mg...
Ziprasidone is a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. The initial evidence suggests an effective dosage range of 80-160 mg/day. Clinical trials suggest that the drug is an effective antipsychotic in schizophrenia and schizoaffective disorder with a benefic...
(including audio-visual hallucinations, delusions, lack of motivation and social withdrawal). Ziprasidone was not found to be carcinogenic in animal tests on mice, rabbits and other animals, and excessive dosage may be harmful to patients with liver function impairment. Therefore, Ziprasidone should ...
In order to ensure use of the lowest effective dose, patients should ordinarily be observed for improvement for several weeks before upward dosage adjustment. Efficacy in schizophrenia was demonstrated in a dose range of 20 mg to 100 mg twice daily in short-term, placebo-controlled clinical ...