An orphan nuclear receptor lacking a zinc-finger DNA-binding domain: interaction with several nuclear receptors. Biochim Biophys Acta. 1997; 1350:27-32. [PubMed: 9003453]Masuda, N., Yasumo, H., Tamura, T., Hashiguchi, N., Furusawa, T., Tsukamoto, T., Sadano, H. and Osumi, T. (...
Journal of Cellular Biochemistry 116 :10.1002/jcb.v116.11, 2435-2444 /Hossain MA, Barrow JJ, Shen Y, Haq MI, Bungert J. Artificial zinc finger DNA binding domains: versatile tools for genome engineering and modulation of gene expression. J Cell Biochem. 2015;116(11):2435-44....
DddA-derived cytosine base editors (DdCBEs) use programmable DNA-binding TALE repeat arrays, rather than CRISPR proteins, a split double-stranded DNA cytidine deaminase (DddA), and a uracil glycosylase inhibitor to mediate C•G-to-T•A editing in nuc
AOBP, a DNA-binding protein in pumpkin, contains a Dof domain that is composed of 52 amino acid residues and is highly conserved in several DNA-binding proteins of higher plants. The Dof domain has a significant resemblance to Cys2/Cys2 zinc finger DNA-binding domains of steroid hormone rec...
Its role in base-recognition correlates with a large, local, protein-induced deformation of the DNA helix at a flexible A-T-A sequence and may give insight into previous mutagenesis experiments. It is apparent from this structure that zinc-finger/DNA recognition is more complex than was ...
Zinc Finger Proteins (ZFPs or ZFs) are human proteins which naturally regulate the genome through sequence-specific interactions with DNA and regulatory proteins. Sangamo’s ZF technologies are composed of a DNA-binding domain and a functional domain (e.g., nuclease, transcription factor). ZF tec...
Zinc Finger Domaindoi:10.1007/3-540-29623-9_9175The zinc finger domain is a DNA-, RNA-or protein-binding protein motif which creates a finger-like loop. The classical C2H2 Zinc finger binds to zinc via two cysteine(C) residues located one in each......
Cover Feature: Comparative Study of Photoswitchable Zinc‐Finger Domain and AT‐Hook Motif for Light‐Controlled Peptide–DNA Binding (Chem. Eur. J. 19/2019)Cover Feature: Comparative Study of Photoswitchable Zinc‐Finger Domain and AT‐Hook Motif for Light‐Controlled Peptide–DNA Binding (Chem. ...
Recombinases have several potential advantages as genome editing tools compared to nucleases and other editing enzymes, but the process of engineering them to efficiently recombine predetermined DNA targets demands considerable investment of time and labor. Here we sought to harness zinc-finger DNA-bindi...
zincproteindomainsdnamediatedinteractions REVIEWPAPER KeepYourFingersOffMyDNA:Protein–ProteinInteractions MediatedbyC2H2ZincFingerDomains KathrynJ.BrayerÆDavidJ.Segal Publishedonline:6February2008 ÓHumanaPressInc.2008 AbstractCys2-His2(C2H2)zincfingerdomains(ZFs) wereoriginallyidentifiedasDNA-bindingdoma...