Therefore, it is possible that some water insoluble ingredients were also extracted by acetone, which may affect the absorption in human, leading to differences in treatment efficacy. An important lesson that we learnt from this study is that, prior to a large scale phase III trial, a smaller...
However, XHLP's specific effective ingredients and mechanism of action against osteoarthritis have not been explored. Therefore, bioinformatics technology and molecular docking technology are employed in this study to explore the molecular basis and mechanism of XHLP in the treatment of knee ...
In the past several decades, studies have indicated that the chemical constituents of Xiaohuoluo pill are abundant and complex to analyze, that the main bioactive ingredients are monoester-type alkaloids and that its main toxic ingredients are diester-diterpenoid alkaloids [27,28]. Therefore, the ...