Dipeptidase inhibitorProline peptideThe inhibitory action of proline-containing peptides such as Gly-Pro, Gly-Pro-Hyp, Pro-Gly, Pro-Gly-Gly, Pro-Pro and Pro-Pro-Pro-Pro ((PrO) 4) on Xaa-Pro-dipeptidylaminopeptidase from pig kidney was investigated. The enzyme activity towards Gly-Pro- ...
In these experiments we knocked down p23 and then exposed cells to 2% O2 in the presence of the proteasome inhibitor MG132 to allow stabilization of hydroxylated HIF-1α. Recombinant VHL was then employed to capture hydroxylated HIF-1α, which was then detected by Western blotting. As before...
coli proline and lysine auxotroph; Isotopic labeling; Interproton distances; Isotope-assisted analysis; Effect of inhibitor binding.HinckAndrewP.EberhardtEricS.EBSCO_AspBiochemistryHinck, A.P.; Eberhardt, E.S.; Markley, J.L. NMR strategy for determining Xaa-Pro peptide bond configurations in ...
Asn-linked oligosaccharides terminating with the sequence SO4-4GalNAc beta 1,4GlcNAc beta 1,2Man alpha (S4GGnM) are present on the glycoprotein hormones lutropin and thyrotropin, pro-opiomelanocortin, and tissue factor pathway inhibitor. The peptide motif ProXaaArg/Lys (PXR/K), which is ...