Five had segmental or multifocal dystonia and parkinsonism: 4 were levodopa‐responsive and 1 non‐levodopa‐responsive. One patient was asymptomatic but had mild bradykinesia. Cutaneous P‐SYN and abnormal DAT scans were noted in the 4 levodopa‐responsive patients and 1 asymptomatic patient. ...
> Section > Chapter Müller, U.; Haberhausen, G.; Wagner, T.; Fairweather, N.D.; Chelly, J.; Monaco, A.P. Genomics 23(1): 114-117 1994 ISSN/ISBN:0888-7543 7829058 10.1006/geno.1994.1465 008418194 Full-Text Article emailed within 0-6 h ...
The locus (DYT3) underlying the X-linked dystonia-parkinsonism syndrome (XDP) was delineated within proximal Xq12-Xq13.1 by analysis of linkage, allelic association, and haplotypes. Short tandem repeat polymorphisms at loci DXS227, DXS559, DXS453, DXS106, DXS339, and DXS135 were studied. The...
X-linked dystonia-parkinsonism (XDP)balance analysisgait analysispresymptomatic phasewearable sensorsBackground:Early diagnosis in patients with neurodegenerative disorders is crucial to initiate disease-modifying therapies at a time point where progressive neurodegeneration can still be modified. Objectives:The ...
X-linked dystonia parkinsonism (XDP) is a neurodegenerative disorder that has received significant interest on several fronts. Although much still remains to be elucidated regarding the disease cause, a robust amount of data has been produced in recent years compared to when it was first described ...
X-linked dystonia-parkinsonism (XDP) is a rare neurodegenerative disease presenting with dystonia at disease onset, followed by parkinsonism in later stages. Neuropathologically, XDP patients show a stage-specific cell loss in the striatum, predominantly affecting medium spiny neurons. The dystonic ...
X-linked dystonia-parkinsonism (XDP) or 'Lubag' is an X-linked recessive disorder primarily seen among Filipino men. This article presents the history, clinical features, genetics, diagnosis, and treatment of XDP.doi:10.1016/B978-0-12-374105-9.00115-5V. Evidente...
Introduction Malnutrition is a leading cause of death for persons living with X-linked dystonia-parkinsonism (XDP), a degenerative disease endemic to the Philippines. Difficulty swallowing has been linked to malnutrition in other populations; however, knowledge of this relationship is limited in XDP. ...
X-linked dystonia-parkinsonismXDPfemale patientdeep brain stimulationimbalanced X-chromosome inactivationAndrea Nichole D. BautistaNeuroscience Institute, Department of Neuroscience and Behavioral Medicine University of Santo Tomas Hospital Manila PhilippinesRaymond L. Rosales...
DystoniaParkinsonismTAF1DYT3LubagActa Neurologica Belgica - X-linked dystonia parkinsonism (XDP) is a rare X-linked recessive degenerative movement disorder that only affects Filipino descent, predominantly males. Its underlying...doi:10.1007/s13760-022-02144-3Chin, Hok Leong...