Key Points: Question: Is the Worst Itch Numeric Rating Scale (WI-NRS) an appropriate tool for quantifying the intensity of pruritus associated with prurigo nodularis? Findings: This secondary analysis of pooled data from the PRIME and PRIME2 clinical trials found that...
Objective We conducted supplementary analyses to assess the psychometric properties of the Worst Itch Numeric Rating Scale (WI‐NRS), the TR03 primary endpoint. Methods Study TR03 was a double‐blind, placebo‐controlled, phase 2 trial in PN patients with documented scores ≥5 on the WI‐NRS ...
Validity of a Single Worst Itch Numeric Rating Scale (WI-NRS) Measurement to Identify Patients with Moderate or Severe CKD-Associated Pruritusdoi:10.1681/ASN.2024k64q3cs2Kieran MccaffertyBarts Health NHS Trust, London, London, United Kingdom;Thilo Schaufler...
Numeric rating scalePatient-reported outcome measuresPruritusPsychometricsBackground Chronic kidney disease-associated pruritus (CKD-aP) is characterized by persistent itch that often leads to substantially impaired quality of life. The Worst Itching Intensity Numerical Rating Scale (WI-NRS) is a single-...