Wnt信号传导径路(Wnt signaling pathway) Wnt信号传导径路β-catenin基因异常癌症摘要:王心不详赵谨不详VIP日本医学介绍
11. Katoh M. WNT/PCP signaling pathway andhuman cancer. Oncol Rep. 2005 Dec;14(6):1583-8. PubMed ID: 16273260 12. Timm A, Grosschedl R. Wnt signaling inlymphopoiesis. Curr Top Microbiol Immunol. 2005;290:225-52. PubMed ID: 16480045 13. Janssens N, Janicot M, Perera T. TheWnt-d...
14. Mathur R, et al. Targeting Wnt pathway in mantle cell lymphoma-initiating cells.J Hematol Oncol. 2015 Jun 6;8:63.15. Chen B, et al. Small molecule-mediated disruption of Wnt-dependent signaling intissue regeneration and cancer. Nat Chem Biol. 2009 Feb;5(2):100-7.16. Huang SM, ...
器官的稳态平衡需要对成体干细胞严格调控,并通过多种信号整合实现干细胞向终末细胞的分化。 Tian, H., et al., Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. Cell Rep, 2015. 11(1): p. 33-42. 当Notch信号受到抑制,小肠干细胞倾向于分化成分泌细胞...
8月22日,来自浙江大学医学院的周天华研究小组在Cell Research杂志发表了题为“Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis”的研究论文。该研究通过整合生物信息学、分子细胞生物学、发育...
20 20 55 卷 V 书面表达 l 20 5O 二总计 86 l0o l65 二、写作为新题型 59.Wnt信 号传 导径路 (Wnt signaling pathway) 1.Wnt的细 胞 内信号 传导径 路概 述 Wnt是 分子 量约4万的分泌型糖蛋白,存在于从线虫、果蝇属到哺 乳动物的各种属生物 中,对动物的早期发育及形态形 成具有重要作用。另...
Wnt signaling pathway and its important role in invertebrate innate immunity are reviewed to provide new clues for the diseases control of invertebrate. Key words: Wnt signaling pathway ;invertebrate ;innate immunity Wnt 信号通路最早在果蝇的发育中被发现,它 在动物间存在遗传学上的高度保守性,且存在于...
[14] Kang AR, et al. A novel RIP1-mediated canonical WNT signaling pathway that promotes colorectal cancer metastasis via β -catenin stabilization-induced EMT. Cancer Gene Ther. 2023 Jul 27. [15] Zhou, et al. Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epit...
RESULTS AND CONCLUSION: Wnt si gnaling pathway is consisted of Wnt/β-catenin signal pathway (Wnt typical signal pathway), Wnt/Ca 2+ signal pathway and Wnt/planar cell polarity signal pathway. Wnt signaling pathway is one of the most important regulatory systems that plays a key role in ...