Opening a new time window for treatment of stroke by targeting HDAC2. J Neurosci. 2017; 37(28):6712-28. https://doi.org/10.1523/JNEUROSCI.0341-17.2017.Lin YH, Dong J, Tang Y, et al. Opening a New Time Window for Treatment of Stroke by Targeting HDAC2. T...
“The stroke burden continues to grow across the world, and particularly in China where stroke is the leading cause of death,” said Xin Cheng (Huashan Hospital of Fudan University/National Center for Neurological Disorders, Shanghai, China), the lead author of the study. “There are...
Despite its effectiveness in improving neurological outcomes, the majority of patients with ischemic stroke are not treated with rtPA, largely because they arrive after the currently approved 3-hour time limit for administration of the medication. One of the potential approaches to increase treatment ...
Stroke treatment is individualized based on the type of stroke, how long symptoms have lasted, how soon a person gets to the hospital, and underlying medical conditions. The best treatment for one situation isn’t the best for another situation. Order of Stroke Treatment and Time Window A stro...
Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need. J Stroke 19: 50-60, 2017... Ike,Dela,Pe?a,... - 《Journal of Stroke》 被引量: 11发表: 2017年 Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic...
Worsening in ischemic stroke patients: is it time for a new strategy? Stroke. 2002;33:1443–5. Article CAS PubMed Google Scholar Lin YH, Dong J, Tang Y, Ni HY, Zhang Y, Su P, et al. Opening a new time window for treatment of stroke by targeting HDAC2. J Neurosci. 2017;37:...
"Stroke is the third leading cause of death in the U.S.," said the study's lead author, William A. Copen, M.D., Director of Advanced Magnetic Resonance Neuroimaging at Massachusetts General Hospital (MGH) in Boston. "Every hour that we can add to the treatment window would allow vastly...
Early treatment of ischemic stroke with thrombolytics is associated with improved outcomes, but few stroke patients receive thrombolytic treatment in part due to the 3-hour time window. Advances in neuroimaging may help to aid in the selection of patients who may still benefit from thrombolytic trea...
H Zhao,G Steinberg - 《Stroke Res Treat》 被引量: 30发表: 2011年 Opening a New Time Window for Treatment of Stroke by Targeting HDAC2. Narrow therapeutic window limits treatments with thrombolysis and neuroprotection for most stroke patients. Widening therapeutic window remains a critical ... Yu...
, and most were excluded because of the time window. In the European Cooperative Acute Stroke Study II (ECASS II) that looked at rt-PA therapy with a treatment window between 0 and 6 hours, more than 80% of patients were treated between 3 and 6 hours and no effect was detected (Hack...