The benefit of hiding such agents of manipulation within the sperm, in the form of functional RNA molecules, is that the manipulation would be invisible to the female until it is too late to prevent fertilisation. The conditions favouring the Trojan horse hypothesis are also probably restrictive,...
Such issues associated with the effective delivery of proteins to tissues has resulted in the search for strategies that protect the protein from degradation/inactivation, thus increasing its half-life and potential efficacy. Nature's way to improve stability has been to encapsulate proteins and RNA ...
He said, “It would be better not to use.“ He said, “Because it makes you a more positive person so that the medicine will work better.” Because by using drugs it interrupts stuff, and […] it [HIV] wasn’t clearing up because I continued to use. Notably, while Wynn missed ...
owing to deletion of one allele or a regulatory mutation; (b) there is an incorrect translational control; (c) there is decreased RNA or protein stability; (d) there is a heterozygous mutation leading to an inactive protein that does not interfere with the wild-type one (no dominant negativ...
Overall, participants would have much preferred to use their HIV medication for them- selves and not sell it. However, it was common for them to be unable to decline the offer to sell medications in times of financial hardship (e.g., after losing a job or when a partner lost his/her/...
‘assembly line’ but interact with each other in complex ways. Nor is the cell obsessed with the economically significant work of ‘manufacturing’ that the metaphor of ‘factory’ would have us believe. Instead, much of the work ...
The decision to keep the FMD-free status with vaccination or move toward a FMD-free without vaccination status depends on several factors, and each country must decide for itself whether to continue or abandon vaccination. This decision needs to be made based on the specific situation and a det...
Though the risk of admission to an intensive care unit is increased due to pediatric comorbidities, it is generally still low for children compared with adults [8]. Age itself also appears to be a risk factor for a more severe course of disease. When children are categorized by age, there...