We report here that the product of the c-Cbl proto-oncogene is prominently tyrosine phosphorylated in response to insulin in 3T3-L1 adipocytes. The tyrosin... V Ribon,AR Saltiel - 《Biochemical Journal》 被引量: 439发表: 1997年 Endurance training improves responsiveness to insulin and modulates...
For a cell of bacterial size, diffusion limitation of glucose influx was negligible. Nevertheless, a significant concentration gradient for one of the enzyme species, nonphosphorylated IIA Glc, was found. This should have consequences because the phosphorylation state of IIA Glc is an important ...
For glycolysis to produce ATP when no oxygen is present, it is necessary for cells to convert ___ to ___. A) pyruvate to glucose B) NADH to ATP C) ATP to NAD+ D) NADH to NAD+ How is coenzyme A formed in glycolysis? Why ...
is dynamically regulated in response to various stimuli and is remarkably similar to phosphorylation [1]. It has been more than 25 years since it was first discovered by Torres and Hart [2]. However, relative development in this field has remained sluggish for almost two...
Why is cellular respiration considered to be an energy-releasing metabolic pathway? Explain how energy is stored in, and released from ATP. How do cells make ATP from glucose without oxygen? 1. How do cells obtain the energy they need to function? 2. What compound is phosphorylated for ATP...
Resemblance between epitopes contained in microbial and host proteins, leading to cross-reactivity of T cells in the host. Original antigenic sin A 'footprint' of immune responses is established during the first exposure to a pathogen. These specific memory T cell populations are preferentially re-...
ZIP4 is found to be upregulated in several types of cancer cells [53, 54, 58]. ZIP6 also plays an important role in numerous cancers, particularly breast cancer [47, 49, 56, 57, 71]. Overexpression of ZnT2 is found to decrease invasive phenotypes of breast cancer cells [72]. In ...
Because this alteration was not sufficient to explain the hyperglycemic phenotype of the offspring, the group decided to study insulin signaling in these animals, as insulin produced by the pancreas enables glucose to enter cells and thereby lowers the level of blood sugar. ...