Mlx-interacting protein (MLXIP, also known as MONDOA)(13614-1-AP) acts as a transcription factor by forming a heterodimer with MLX protein. This complex binds to and activates transcription from CACGTG E boxes,
Why does a cell need so many different kinds of enzymes? What kind of reaction does the protease enzyme catalyze? Explain the following enzyme and what type of reaction they catalyze: (a) Hexokinase (b) Phosphoglycerate mutase Why can a gluco...
Read the following statement below and explain your answer: Enzymes that catalyze reactions in which a molecule is phosphorylated are usually called "kinases". Hexokinase catalyzes the phosphorylation of glucose (a "hexose", because it is a 6-carbon suga En...
and protein localization. Phosphorylation is catalyzed by phosphatases and can be reversible – phosphorylated proteins can be dephosphorylated by protein dephosphatases. The addition of a single phosphoryl group adds +/- 1 kDa to the MW, which is often...
ZIP14 and ZIP4 were also found to be involved in diabetes as altered zinc traffick- ing in Zip14−/− mice resulted in a phenotype with defects in glucose homeostasis [45], and in the murine pancre- atic beta cell line MIN6, overexpression of ZIP4 leads to increased granular zinc ...
Specifically, we detail how human AD pathology is mirrored in current transgenic mouse models (“What”) and describe the critical need for introducing human APOE into these mouse models (“Who”). We next outline different methods for introducing human APOE into mice (“How”) and highlight ...
During anaerobic glycolysis, each molecule of glucose produces how many molecules of ATP? Why does the Krebs cycle need oxygen? How does the electron transport chain change when NADH and FADH2 donate their electrons to complex 1 or 2? ...
Why do you need to shake a suspension? Why does milk have a pH of about 7? Explain why protonation of pyrrole occurs at C2 to form A, rather than on the N atom to form B. Why is H2O(g) usually called water vapor? Why is anionic polymerization used to form block copolymers? Why ...
Explain, with examples, why do we need ATP. What two roles does ATP hydrolysis play in muscle contraction? 1. What is ATP? 2. What is ADP? 3. Why does energy need to be transferred from glucose to ATP? Explain why ATP is abundant in energy. Why do organisms need ATP for metabolic...
glucose intolerance The normal range for the carbonyl of a ketone is 1715 cm-1. Why does the carbonyl peak for cyclopentanone appear at 1750 cm-1? a.) ring strain b.) conjugation c.) overtones d.) electronegativity effects How would you ...