Mlx-interacting protein (MLXIP, also known as MONDOA)(13614-1-AP) acts as a transcription factor by forming a heterodimer with MLX protein. This complex binds to and activates transcription from CACGTG E boxes, playing a role in the transcriptional ...
Why does a cell need so many different kinds of enzymes? What kind of reaction does the protease enzyme catalyze? Explain the following enzyme and what type of reaction they catalyze: (a) Hexokinase (b) Phosphoglycerate mutase Why can a gluco...
Protein precursors need to be processed by proteases in order to engender a functional product (without pro-peptide). Figure 2: PINK1 (23274-1-AP) is a mitochondrial serine/threonine-protein kinase that protects cells from stress-induced mitochondrial d...
During anaerobic glycolysis, each molecule of glucose produces how many molecules of ATP? Why does the Krebs cycle need oxygen? How does the electron transport chain change when NADH and FADH2 donate their electrons to complex 1 or 2? ...
ZIP14 and ZIP4 were also found to be involved in diabetes as altered zinc traffick- ing in Zip14−/− mice resulted in a phenotype with defects in glucose homeostasis [45], and in the murine pancre- atic beta cell line MIN6, overexpression of ZIP4 leads to increased granular zinc ...
Specifically, we detail how human AD pathology is mirrored in current transgenic mouse models (“What”) and describe the critical need for introducing human APOE into these mouse models (“Who”). We next outline different methods for introducing human APOE into mice (“How”) and highlight ...
Their task was to show the FDA enough evidence to convince them that the fiber has at least one “beneficial physiological effect to human health,” the agency explains—such as lowering blood glucose, lowering cholesterol levels, lowering blood pressure, increasing the frequency of bowel movements...
Read the following statement below and explain your answer: Enzymes that catalyze reactions in which a molecule is phosphorylated are usually called "kinases". Hexokinase catalyzes the phosphorylation of glucose (a "hexose", because it is a 6-carbon suga En...
Explain, with examples, why do we need ATP. What two roles does ATP hydrolysis play in muscle contraction? 1. What is ATP? 2. What is ADP? 3. Why does energy need to be transferred from glucose to ATP? Explain why ATP is abundant in energy. Why do organisms need ATP for metabolic...
Glycogen phosphorylase is inactivated by the allosteric binding of glucose in the liver. What does the allosteric binding of AMP to glycogen phosphorylase do to it in the muscle? A. causes it to adopt the lower affinity tense state...