Muriel Rhinn, the first author of the study, adds, “While cellular senescence has long been associated with aging and age-related disease, we now show that aberrant induction of senescence can also contribute to developmental defects. As valproic acid is strongly linked to cognitive defects and ...
Why is gene expression regulated in prokaryotic cells? Why are restriction enzymes only in prokaryotes? Why don't NRTIs stop normal DNA replication? Why doesn't an RNA virus have methylation? Why does DNA get condensed into chromosomes during cell division? Why are ribosomal RNA genes conserved?
Why does it happen? What can happen if there is mutation of DNA for the production of proteins? What are some examples? Mutations DNA replication is a complex and drawn-out process in eukaryotes. During this process, the...
(a) ErmC expression does not affect ribosome assembly. Sucrose gradient profiles of ribosomal subunits from S. aureus RN4220 cells transformed with pLI50 or pErmCC plasmids. (b) Effect of dimethylation of A2058 on abundance of cellular proteins. Two-dimensional difference gel electrophoresis ...
Two pathways degrade mRNA: 1) 5′ to 3′ exonuclease reaction mediated by Xrn1p after de-capping of 5'-methylguanosin; 2) 3' to 5' digestion mediated by a nuclear multi-protein complex called exosome after the removal of polyA tail, which does not require the removal of the 5'-cap ...
“Wait… reducing protein without reducing calories does the same thing. We must eat less protein to live longer!” “Well I’ll be darned! The whole ‘life extension’ thing works just by limiting methionine. Methionine bad. Other amino acids okay! Down with meat!” ...