Section of Ophthalmology and Neuroscience, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK James A Poulter, Walid El-Sayed, Chris F Inglehearn & Alan J Mighell Department of Oral Biology, Dental School, Suez Canal University, Ismailia, Egypt Walid El-Sayed Department of ...
Liu, SixinMartin, Kyle ESnelling, Warren MLong, RoseannaLeeds, Timothy DVallejo, Roger LWiens, Gregory DPalti, YnivG3: Genes | Genomes | Genetics
Previous large-scale sequencing projects have identified many putative cancer genes, but most efforts have concentrated on mutations and copy-number alterations in protein-coding genes, mainly using whole-exome sequencing and single-nucleotide polymorphism arrays1,2,3,4. Whole-genome sequencing has made...
Leeds has been at the forefront of digital pathology and AI research and innovation for more than 15 years, with St James University Hospital being one of the world’s first fully digital pathology labs. Successes at Leeds are being used as a blueprint for deployment ...
Leeds Institute of Cancer and Pathology, Section of Tumour Biology and Pathology, Leeds University, Leeds, UK Morag Taylor, Emma Tinkler-Hundal, Katie Southward & Phil Quirke Almac Diagnostics, Craigavon, Northern Ireland, UK Paul Medlow, Keith McGreeghan-Crosby, Iris Halfpenny & Katherine E Kea...
Computational analysis of cancer genome sequencing data Article08 December 2021 The repertoire of mutational signatures in human cancer ArticleOpen access05 February 2020 Main Cancer is the second most-frequent cause of death worldwide, killing more than 8 million people every year; the incidence of ...
whole-genome sequencingtransmissionsurveillanceBackground. Variation in Clostridium difficile infection (CDI) rates between healthcare institutions suggests overall incidence could be reduced if the lowest rates could be achieved more widely.Eyre, David W....
ARTICLE Received 30 Nov 2013 | Accepted 28 Mar 2014 | Published 29 Apr 2014 | Updated 10 Oct 2014 DOI: 10.1038/ncomms4756 OPEN Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden J.-B. Cazier1,2, S.R. Rao3,4,...
Whole-genome sequencing dataset We analyzed Illumina whole-genome paired-end sequencing reads (100–150 bp) from 2,954 tumors and matched normal samples across 38 cancer types21. On the basis of the robustness of the retrotransposition calls (false discovery rate of <5%), we opted to ...
457. McGill University and Genome Quebec Innovation Centre, Montreal, QC H3A 0G1, Canada. 458. Centre National de Génotypage, CEA - Institute de Génomique, Evry 91000, France. 459. Leeds Institute of Medical Research @ St James's, University of Leeds, St James's University ...