A whole-genome association study ofShifman, S., Bhomra, A., Smiley, S., Wray, N. R., James, M. R., Martin, N. G., . . . Flint, J. (2008). A whole genome association study of neu- roticism using DNA pooling. Molecular Psychiatry, 13, 302-312....
We performed a whole genome association study (WGAS) in 2466 Black participants from JHS on 30,672,656 variants limited to an allele count of at least five against 2291 metabolites (337 known metabolites and 1954 unknown metabolites peaks; Fig.1). Clinical characteristics of the study population...
A whole genome association study of global gene expression. Nat Genet (in press)Dixon, A.L., Liang, L., Moffatt, M.F., Chen, W., Heath, S., Wong, K.C.C., Taylor, J., Gut, I., Farrall, M., Lathrop, G.M. et al. (2007) A whole-genome association study of global gene...
A whole genome association study of neuroticism using DNA pooling. Molecular Psychiatry 13, 302-312.Shifman S, Bhomra A, Smiley S, Wray NR, James MR, Martin NG, Hettema JM, An SS, Neale MC, van den Oord EJ, Kendler KS, Chen X, Boomsma DI, Middeldorp CM, Hottenga JJ, Slagboom ...
RESEARCH Open Access A whole genome association study of mother-to-child transmission of HIV in Malawi 来自 Citeseer 喜欢 0 阅读量: 24 作者:BR Joubert,EM Lange,N Franceschini,V Mwapasa,KE North,SR Meshnick 摘要: Background: More than 300,000 children are newly infected with HIV each year...
Makoto Matsuoka and colleagues use a whole-genome sequencing-based approach to perform genome-wide association analysis for important agronomic traits in rice. Using phenotypically diverse rice with low interrelationships, they rapidly identify novel genes associated with heading date, plant height and pani...
Whole genome sequencing was then performed on the 93 patients who had imaging features consistent with thoracic aortic disease and the 126 patients with a normal descending thoracic aorta. Results The results of this study suggest one variant-level, four gene-level, and one gene set-level ...
Genome-wide association study (GWAS) Genotyping by Sequencing (GBS) Genomic Data Analysis WGS Sequencing Metrics Depth The sequencing depth, one of the key metrics used to assess volume in genomics, is defined as the ratio of the total recorded base pairs (bp) to the size of the genome. Th...
We analyze the genetic relationships by whole-genome resequencing of 36 wild mice and 36 inbred strains. All classical inbred mice cluster together distinctly from wild and wild-derived inbred mice. Using nucleotide diversity analysis, Fst, and XP-CLR, we identify 339 positively selected genes that...
A genome-wide association study (GWAS) can be a powerful tool for the identification of genes associated with agronomic traits in crop species, but it is often hindered by population structure and the large extent of linkage disequilibrium. In this study, we identified agronomically important genes...