Whole-exome sequencing (WES) has become the strategy of choice to identify causal variants in monogenic disorders. However, the list of candidate variants can be quite large, including false positives generated by sequencing errors. To reduce this list of candidate variants to the most relevant ...
Whole exome sequencing is a powerful tool to investigate genetic variations underlying cancers, Mendelian diseases, and complex human disorders.
the Ion Proton Sequencer provides a simple, scalable, and affordable solution for whole exome sequencing in cancer research. Combined with theIon Chef Systemfor automated template preparation and the integrated Ion Reporter workflows for data analysis, the Ion Proton System is an excelle...
Fast and scalable exome sequencing “Speed is important for our service. But so is daily processing of exomes without batching. Ion Torrent platform offers us both.” Dr. Sara Alvarez, Medical Director NIMGenetics, Spain Simple, efficient exome enrichment—s...
Learn about whole exome sequencing (WES), a targeted next generation sequencing method that identifies all the protein-coding genes (exons) in the genome.
www.nature.com/scientificreports OPEN received: 21 August 2015 accepted: 14 December 2015 Published: 20 January 2016 Whole-exome Sequencing Analysis Identifies Mutations in the EYS Gene in Retinitis Pigmentosa in the Indian Population Yanan Di1,2,3,7,*, Lulin Huang2,3,7,*, Periasamy...
Whole exome sequencing (WES) enables the analysis of all protein coding sequences in the human genome. This technology enables the investigation of cancer-related genetic aberrations that are predominantly located in the exonic regions. WES delivers high-throughput results at a reasonable price. Here...
Sequencing & analysis IDT ALIGN℠Program Method data Library preparation and hybridization capture To assess the xGen Exome Hyb Panel v2, twelve libraries were prepared using 100 ng of human genomic DNA (Coriell Institute). Then, xGen Stubby Adapters and Unique Dual Indexing primers (UDIs) were...
exome sequencing Although the exome comprises less than 1% o the genome, it contains more than 85% o known disease-causing mutations [1]. Until the cost and complexity o whole-genome sequencing is reduced, whole-exome sequencing provides a cost-e ective alternative to traditional methods or...
Global Whole Exome Sequencing Market, by Geography, 2013 – 2018 Source: MarketsandMarkets Analysis This global whole exome sequencing market was valued at $326.6 million in 2013 and is expected to grow at a CAGR of 22.0% from 2013 to 2018, to reach $884.1 million by 2018. The market is...