WHITE-tailed deerPRION geneticsGENETIC polymorphismsGENE amplificationPrPvariation at residue 96 (G/S) plays an important role in the epidemiology of chronic wasting disease (CWD) in exposed white-tailed deer populations. In vivo studies have demonstrated the protective effect of serine at codon 96,...
To evaluate RT-QuIC using blood as CWD diagnostic sample, the present study compared the sensitivity and specificity of RT-QuIC on blood collected from CWD-positive and CWD-negative white-tailed deer harvested by hunters under different assay conditions, including NaCl as the main ionic component ...
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy, which can affect white-tailed deer (Odocoileus virginianus). Transmission of CWD is facilitated by proximal contact between infected and susceptible individuals; therefore, movement of infected individuals, both within and ...
Mule deer, white-tailed deer, and Rocky Mountain elk are the major known natural hosts for CWD. In 2005, a hunter-killed moose was confirmed with CWD in Colorado, suggesting that this member of the deer family too is a natural host. The disease was first identified as a fatal wasting sy...
In white-tailed deer (Odocoileus virginianus), closely related females form social groups, avoiding other social groups. Consequently, females infected with chronic wasting disease (CWD) are more likely to infect social group members. Culling has been used to reduce CWD transmission in high-risk are...
White-tailed deer fawns were obtained from a farm that has never had a case of chronic wasting disease and is located outside of a CWD endemic area. Deer were inoculated intracerebrally with 1 mL of inoculum (n = 5) or were maintained as non-inoculated controls (n = 1). Inoculated ...
In North America, hunting and farming industries focused on the processing and consumption of white-tailed deer (WTD) venison are particularly vulnerable to CWD prion contamination, as millions of WTD are consumed annually. Real-time quaking-induced conversion (RT-QuIC) is a highly sensitive assay...
product of protein misfolding cyclic amplification (PMCA) applied directly into real-time quaking induced conversion (RT-QuIC) [denoted now as PQ] to demonstrate the presence of prion seeding activity (i.e. prions) in ~55% of hamstring muscles harvested from CWD-positive white-tailed deer. Th...
In white-tailed deer (Odocoileus virginianus), closely related females form social groups, avoiding other social groups. Consequently, females infected with chronic wasting disease (CWD) are more likely to infect social group members. Culling has been used to reduce CWD transmission in high-risk are...
WHITE-tailed deerLYMPHOID tissueBIOPSYEXTERNAL earEfforts to contain the spread of chronic wasting disease (CWD), a fatal, contagious prion disease of cer... NC Ferreira,JM Charco,J Plagenz,... - 《Scientific Reports》 被引量: 0发表: 2021年 Comparison of Chronic Wasting Disease Detection Meth...