In this study, we developed and characterized recombinant human erythropoietin (EPO) producer cell lines. Three kinds of hprt gene-targeting vectors with a different EPO expression cassette were constructed. The one kind of the vector, phprt-IVS-GT-EPO #52 (#52), has both EPO cDNA sequence ...
Renin-Angiotensin-Aldosterone System: The Renin-Angiotensin-Aldosterone System is a complex multi-organ hormone system that plays a role in the regulation of blood pressure. It regulates sodium and water absorption in the kidney. It is activated by a d...
In this study, we developed and characterized recombinant human erythropoietin (EPO) producer cell lines. Three kinds of hprt gene-targeting vectors with a different EPO expression cassette were constructed. The one kind of the vector, phprt-IVS-GT-EPO #52 (#52), has both EPO cDNA sequence ...
PURPOSE: A conjugate containing carboxylic acid and non-antigenic hydrophilic biocompatible polymer is provided to minimize physiological activity reduction of erythropoietin and to enhance drug efficiency in the human body.;CONSTITUTION: A conjugated of biocompatible polymer and EPO(erythropoietin) is ...
Characterization of the Erythropoietin (EPO) Protein Production in the Recombinant Human Cultured Cells, in which the Exogenous EPO Gene was Introduced into Hypoxanthine Phosphoribosyl Transferase (HPMammalian cell expression systems are widely used for production of therapeutic proteins. Industrial production...
Methods for treating diseases associated with Erythropoietin (EPO) comprise administering one or more oligonucleotide compounds designed to inhibit the EPO natural antisense transcript to patients.ジョゼフカラードオルガコルコヴァシャーマン
The present Invention relates to the fields of Genetic Engineering and BiotechnologyAnd more specifically with the transgenic animals.This Invention aims to obtain a line of MICE capable of producing Human Erythropoietin in the Milk of their females.Its Essence is that the Genome of a line of ...
TRANSGENIC RABBITS WHICH EXPRESS HUMAN ERYTHROPOIETIN (EPOH) IN THE MILK OF THE FEMALESThe present Invention relates to the fields of Genetic Engineering and BiotechnologyAnd more specifically with the transgenic animals.This Invention aims to obtain a line of Rabbits capable of producing Foreign ...