Kirkin, V, Mazitschek, R, Krishnan, J (2001) Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2. Eur J Biochem 268: pp. 5530-5540Kirkin V,Mazitschek R,Krishnan J,et al.Characterization of indolinones which...
et al. The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231. Nucleic Acids Res. 15, 5963–5971 (1987). Article CAS Google Scholar Naldini, A. & Carraro, F. Role of inflammatory mediators in angiogenesis. Curr. Drug ...
Inflammatory bowel disease (IBD), a chronic relapsing gastrointestinal inflammatory disease, mainly comprises ulcerative colitis (UC) and Crohn’s disease (CD). Although the mechanisms and pathways of IBD have been widely examined in recent decades, its
The initial results of cell culture and animal studies determine that this well-known drugs not only maintain an excellent safety profile but also act as a promising drug candidate in fighting COVID-19. However, more experimental data are needed to extensively use it to treat patients suffering ...
The actual performance of your ambulatory proper care local drugstore efficiency Posted onJanuary 15, 2025 Reply Conclusions procedures and outcomes of the task, will provide evidence in order to use the UP in a broader populace with advertising along with other psychological disorders also covered ...
The invention provides nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF) and its receptor c-met. The nucleic acid ligands of the instant invention are isolated using the SELEX method. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic...
The present invention also relates to an Aggrus-CLEC-2 binding inhibitor containing a peptide comprising the region of Aggrus, or a monoclonal antibody, and a pharmaceutical composition comprising the same. The present invention further relates to a method for screening for a drug by using ...
drug conjugate. 15 As described above, it has been reported that a peptide containing the synthetic motif CGH, derived from the metal ion binding motif GGH that is frequently found in vivo, binds metal ions and inhibits the sulfonation of cysteine (Van Horn et al. (2003) J. Biol. Inorg....
Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents.
01 August 2016 Koji Nagahama, Tomoya Utsumi, Takayuki Kumano, Saeko Maekawa, Naho Oyama & Junji Kawakami Curcumin has received immense attention over the past decades because of its diverse biological activities and recognized as a promising drug candidate in a large number of diseases...