Recently, the ability of tumor cells to adapt their metabolism has been associated to resistance to therapies. In this study, we first described the metabolic reprogramming of Non-Small Cell Lung Cancer (NSCLC)
Hylan A and B are derivatives of hyaluronic acid. It is... View Device InformationOrthovisc Orthovisc(R) is a high molecular weight hyaluronic acid preparation, from bacterial cells, which makes it safe for patients suffering from avian allergies such as to birds, eggs and/or feathers... ...
For example, immunotherapy application represented by PD1 inhibitors is limited in pancreatic cancer due to the special “cold” tumor immune microenvironment [9]. Therefore, novel breakthroughs are crucially needed in the judgment and treatment of pancreatic cancer, particularly from the perspective of ...
When a patient has a squamous cell carcinoma, this is derived from what type of tissue? Which body tissue is found underlying all epithelial tissues and functions to hold organs in place? A malignant tumor has all of the following c...
Although the available data regarding trained immunity in the context of breast cancer cell elimination is scarce, this study presents the potential of this immune adaptation pathway utilizing magnetic nanoparticles.Due to their comparable characteristics, swine are frequently utilized as a model for ...
Exosomes are systemic messengers that can deliver their cargoes over varying distances, with important physiological roles in the maintenance of cellular homeostasis [67], regulation of an immune response, and even as key mediators of developmental signaling [49, 83, 84]. In a pathological context,...
Which type of cells shows the mitotic cell division? What are some characteristics of the different types of cell division? What type of cell division occurs in somatic cells of multi-celled organisms (non-sex cells) and occurs for growth and developmen...
Once exposed or released from cells, DAMPs are able to interact with membrane bound or vesicular pattern-recognition receptors (PRRs) [15] [11]. At the same time, tumor cells undergoing immunogenic apoptosis downregulate the expression of “don't eat me” signals, such as surface integrin-...
Transfer of ETV6- NTRK3 retrovirus into mouse mammary epithelial cells produced tumor-prone transformed cells in nude mice, but it is not clear whether the gene can drive tumo- rigenesis on its own or if additional modifications are required [6]. SBCs generally have an indolent clinical ...
Recent studies on raft signaling microdomains have progressed in various fields, and our knowledge of their characteristics and cellular functions has been accumulating. Rafts are lateral assemblies of GSL and cholesterol that associate with specific proteins, and they are thought to be platforms serving...