Metastasis is defined by the capacity of tumoral cells to leave the primary tumor, migrate and become implanted in a distant organ, then to proliferate, thus forming new tumoral sites. Metastatic dissemination is related to the local invasiveness of the tumoral cells in tissues. This invasiveness ...
Background Angiogenesis, crucial for tumor progression, is a process regulated in the tissue micro-environment. Vascular endothelial growth factor (VEGF) i... S Garvin,C Dabrosin - 《Bmc Cancer》 被引量: 80发表: 2008年 In vivo quantitative imaging of normal and cancerous breast tissue using ...
High frequency of promoter hypermethylation of RASSF1A in tumorous and non-tumourous tissue of breast cancer To determine the presence of RASSF1A promoter methylation in tumorous and non-tumorous tissues of breast cancer. Methylation-specific PCR was used to detec... W Yeo,Wong, Wai-Lap,N ...
Chemotherapy: Use of powerful chemicals to kill cancer cells in the human body. Malignant: A usually fast-growing, often fatal tumor that invades surrounding tissue and sheds cells that spread throughout the body, creating new tumors. Metastasis: Spreading of a cancerous growth by shedding cel...
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and immune checkpoint inhibitors (ICIs), have obtained durable clinical responses, but
{\prime} }}}\)—of normal and cancerous breast tissues that best matched surface temperatures observed on IR images. Clinical data consisted of high-resolution IR images, three-dimensional (3D) breast surface geometries, and internal tumor definition from a female subject histologically diagnosed ...
In this study, the patient recruitment was performed following the criteria, i.e., the patient with non-small cell lung carcinoma (NSCLC) histology and availability of sufficient cancerous tissues for the extensive studies. Following the criteria, 17 patients with MET exon 14 skipping mutation tu...
It is noteworthy that low birth weight is associated with insulin metabolism disorders in adulthood, and this conclusion has generated widespread discussion. Both in vivo and in vitro studies have reported that insulin may promote precancerous lesions and tumor growth in colon cancer [32,33]. Addi...
Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunofluorometry and immunohistochemistry Human kallikrein 4 (gene, KLK4; protein, hK4), a recently discovered member of the kallikrein gene family, shares many characteristics with prostate-specif... CV Obiezu,S ...
The researchers found that tumors from younger patients showed advanced signs of aging. For example, they discovered younger patients' tumors had biological ages older than the chronological age of matched non-cancerous tissue as measured by tags, called DNA methylation marks. These marks alter gene...