Increased expression of osteoclast differentiation factors RANKL is known to occur in the synovial membrane of chronically OA joints, leading to secondary bone resorption39, 100. In similar context, another group recently investigated the expression of bone resorption genes in OA and OP, in relation ...
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With chronic exposure, one may also start to decipher the primary responses and the potential secondary responses due to the complexity of the potential interactions. A number of responses of astronauts to living in LEO conditions have been noted (Table 1); however, the individual responses are ...