The Unfolding Protein Response (UPR) located within the Endoplasmic Reticulum protects against the pathological effects of abnormal proteins made in neurodegenerative diseases by activating three main stress sensors that are responsible for the refolding and/or degradation of proteins and apoptosis. ...
What proteins are fundamental to the immune system? What role do endothelial cells play in maintaining arterial health? Do active and passive immunity belong to the adaptive immune system? If yes, do they belong to the humoral or cellular immunity?
Stem cells have a unique feature that reduces the likelihood of rejection by the recipient’s immune system. They are able to evade immune detection and avoid attacks by the recipient’s immune system. Stem cells have a low level of expression of major histocompatibility complex (MHC) molecules,...
gondii are crucial for the infection of animal and human hosts. Its proteins are tagged with carbohydrates to stabilize and transport them, critical to completing the T. gondii life cycle. Carbohydrate antigens are recognized by the host’s immune system, eliciting carbohydrate-specific antibodies, ...
Proto-oncogenes are normal genes that can lead to cancer if they are mutated or expressed at abnormally high levels. The main...
NODs: Intracellular proteins involved in inflammation and apoptosis Nat. Rev. Immunol., 3 (2003), pp. 371-382 CrossrefView in ScopusGoogle Scholar [98] P. Rosenstiel, M. Fantini, K. Brautigam, T. Kuhbacher, G.H. Waetzig, D. Seegert, S. Schreiber TNF-alpha and IFN-gamma regulate the...
proteins through protein-protein interaction of death folds (a tertiary structure motif). Executioner caspases carry out the mass proteolysis that leads to apoptosis. These caspases can cleave a wide range of target proteins leading to apoptosis. Caspase-activated DNase (CAD/DFF40) is the main ...
The compounds that can resist the digestion and reach the colon are resistant carbohydrates, lipids, proteins and some bioactive compounds. Carbohydrates that are able to reach the colon during the digetion process are called Resistant Carbohydrates (RC) and are also known for being the preferred ...
During DNA replication DNA is replicated, as well as the associated proteins with DNA such as histones and nucleosomes.Answer and Explanation: Proofreading is an act that occurs via exonucleases and polymerase enzymes during DNA replication. These enzymes are responsible for ensuring the......
This type of immunotherapy is one of the most effective cancer immunotherapy as it involve the use of proteins that are made by the cells of the body as it also helps in playing a vital role in the normal immune responses. This protein also enhances the ability to respond to the cancer ...