The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth and...
Proteins are large, polymorphous macromolecules that provide an array of structural and functional aspects to the body. Most body structures are comprised of proteins as well as all enzymes. Proteins are made up of smaller sub-units called amino acids in which the sequence of amino acids in a ...
While at first sight, the extracellular matrices of plant and animals do not have much in common, a closer look reveals remarkable similarities. In particular, the proteins involved in the adhesion of the cell to the extracellular matrix share many functional properties. At the sequence level, ...
What is the structure that is only available in animal cells? What is a cell? What are the functions of a cell? What makes cells different from each other? What is a nucleus in a cell? Which is a living cell without a nucleus?
But even that genomic arrangement is controlled by other upstream genes and proteins. Could those regulatory molecules be considered the true root of cell types? Günter Wagner, an evolutionary biologist at the University of Vienna, Austria, thinks so. Wagner and...
Characterize a broader range of cell signaling parameters: Western Blot is limited to measuring the phosphorylation state of proteins. In-Cell ELISA can also measure protein localization, interaction, and degradation. More effective protein analysis: The assay can be performed in adherent or suspens...
Inside of these nanoparticles, there is genetic information, sugars and proteins, that are like the texts that one cell sends to the other and are read in order to elicit a response. They come from both healthy cells and diseased cells. What is interesting is that ...
Proteins are complex structures in the body. Here, the brightly colored and twisty blobs represent different immune system proteins on the outer layer of a T-cell, a type of white blood cell that helps the body to identify foreign invaders.(Image credit: JUAN GAERTNER/SCIENCE PHOTO LIBRARY via...
a small GTPase, provide the energy that drives transport into the nucleus. But so many proteins ...
new cells. However when the DNA of the cell is damaged, for example when there is a genetic change such as DNA mutation or defective protein synthesis, the cell becomes abnormal. It begins to divide uncontrollably and forms a growth (cancerous tumour), in contrast to the normal cell in ...