In the decade of new therapeutic options for myelodysplastic syndromes (MDS), it is more important than ever to recognize how to diagnose the disease and classify the patients into a subtype or risk stratification that allows predicting prognosis and, more importantly, developing treatment strategy ...
Blood Hematopoietic Disease:Bone marrow Dysplasia Syndrome (MDS) Disease which is close to the early stage of leukemia. May be developed as the complicating disease of cancer radiation treatment. Symptoms areanemia, bleeding, and infection disease. The case which advances to AML from MDS is a adv...
Primary myelofibrosis is a disease in which abnormal blood cells and fibers build up inside the bone marrow.Prognosis Certain factors affect prognosis (chance of recovery) and treatment options for primary myelofibrosis. Prognosis depends on the following:...
Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our science team must pass long technical science tests, difficult logical reasoning and...
Researchers are studying if TGF-b increases VEGF, by increasing the hypoxia-inducible factor, which may make tumors spread [27, 28]. In one human study, an elevated blood level of TGF-b was correlated with lymph node metastasis and poor prognosis in patients with gastric cancer. This finding...
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(MDS)), prognosis is poor. These patients have been the target of recent clinical development in AML. At ASCO 2016 we will see the pivotal results for a novel chemotherapeutic, Vyxeos™ (CPX-351, Celator Pharmaceuticals), which could transform care for a subset of patients. Vyxeos is a...
Anemia in MDS is due t... V Santini - 《Seminars in Hematology》 被引量: 16发表: 2015年 Rationale and design of oBservational clinical Research In chronic kidney disease patients with renal anemia: renal proGnosis in patients with Hyporesponsi... Renal anemia is an important complication in ...
The myelodysplastic syndromes. Part I. What are they? Part II. Classification. The FAB classification provides a useful framework for the study of the MDS: it permits the comparison of different series in respect of clinical and laboratory findings, prognosis and response to treatment, and of fun...
Based on their mechanisms of action and available clinical data, immunotherapy agents may provide greatest clinical benefit if used as early as possible in the treatment paradigm when patients have a better prognosis. Furthermore, patients who eventually undergo disease progression after immunotherapy may...