The survival of MDS patients was poor, with an observed 3-year survival rate of only 35% (5-year survival data were not available at the time of the current report). Male patients and patients who were diagnosed at an older age had significantly worse survival. MDS survival also varied ...
The Kaplan-Meier method and the multivariate Cox regression model were used to examine whether gender disparity in the survival of patients with MDS existed. We found that male patients had higher incidence rate of MDS (55.3% vs 44.7%, P<0.001) and a significant survival disadvantage (27.6% ...
Each 6-month segment has its own study-specific hazard rate and therefore also its own HR for MRD-negative vs MRD-positive groups.12 Studies that reported the observed HRs depending on MRD status and the associated CIs (type 2 data) contribute directly to the probability distributions of the ...
When patients were excluded for pre- and post-MDS, the 1-year survival rate was 59.5% (95% CI, 55.8%-63.0%) in the pre-approval arm and 69.4% (95% CI< 67.5%-71.1%) in the post-approval arm (adjusted HR, 1.13; 95% CI, 0.98-1.3). With the exclusion of patients ...
The 5-year survival rate for patients with moderately differentiated squamous cell carcinomas (MDSCC) is 2.41 times higher than the rate for other morphological types but the difference is not statistically significant (OR- 2.41 CI-95%; P-0.31). Table 2. Characteristics of OSCC patients overall...
with radiation and/or chemotherapy differs from de novo MDS, in that it has a high frequency of chromosomal abnormalities (typically in the context of complex karyotype), a high rate of transformation to acute myeloid leukemia, and substantial resistance to the standard therapy used to treat MDS...
Among 17 patients transplanted within 3 months of first transplant, mortality was 100% and median survival was 2.3 months. MA transplantation within 3 months of prior SCT carries an unacceptably high rate of NRM. NMA second transplants were associated with substantially less NRM and despite a ...
cycle3. It has been suggested that dry-down and/or rapid rehydration of soils via rain can cause cell death14, which in turn would necessitate rapid growth in the short window of rain-induced activity for maintaining desert soil microbial communities. However, in situ growth rate data from de...
The relapse-free survival (RFS) rate was 77% in the cohort of patients who received Orca-T vs 62% in the cohort of patients who received PTCy (HR, 0.5; 95% CI, 0.3-0.9). Furthermore, the non-relapse mortality (NRM) rates with Orca-T and PTCy were 3% and 16%, respectively (HR...
Among the Bx profiles, however, transplants from Bx1 donors were associated with a risk for survival of AML/MDS patients in CR1. The survival rate was even worse than that observed in transplants from AA donors. There are KIRs including 3DS1, 2DL5A, 2DS5, and 2DS1 on the telomeric ...